The transdermal route of administration provides numerous advantages over conventional
routes ie, oral or injectable for the treatment of different diseases and cosmetics applications …

Transdermal devices are used to deliver drugs through the skin. However, limitations such
as molecular weight and hydrophilicity of the molecules prevent its wider use. Microneedle …

Microneedle arrays (MNAs) are small patches containing hundreds of short projections that
deliver signals directly to dermal layers without causing pain. These technologies are of …

In the decade since their advent, ablative fractional lasers have emerged as powerful tools
to enhance drug delivery to and through the skin. Effective and highly customizable, laser …

Abstract mPEG-PLA and PLA-PEG-PLA copolymeric nanoparticles with three different PLA
to PEG ratios are synthesized and used for encapsulation of recombinant human Growth …

Introduction Topical drug delivery is highly attractive and yet faces tissue barrier challenges.
Different physical and chemical methods have been explored to facilitate topical drug …

Microneedle arrays (MAs) are among the most promising transdermal drug delivery systems
in the last decades due to its minimally invasive nature, convenient operation, and first-pass …

The present study investigated the transdermal delivery of donepezil hydrochloride across
dermatomed porcine ear skin using passive and physical enhancement techniques. In vitro …

Topical therapy of superficial fungal infections allows the prevention of systemic side effects
and provides drug targeting at the site of disease. However, an appropriate drug …

Baclofen, a GABAb agonist, is used in the treatment of multiple sclerosis, a
neurodegenerative disease. Currently available dosage forms to deliver baclofen are …