Blood-based biomarkers in the diagnosis of Chronic Traumatic Encephalopathy: research to date and future directions

MJ Halicki, K Hind, PL Chazot - International Journal of Molecular …, 2023 - mdpi.com
Chronic Traumatic Encephalopathy (CTE) is a neurodegenerative disease consistently
associated with repetitive traumatic brain injuries (TBIs), which makes multiple professions …

Fluid biomarkers of chronic traumatic brain injury

S Friberg, C Lindblad, FA Zeiler, H Zetterberg… - Nature Reviews …, 2024 - nature.com
Traumatic brain injury (TBI) is a leading cause of long-term disability across the world.
Evidence for the usefulness of imaging and fluid biomarkers to predict outcomes and screen …

Plasma phosphorylated tau181 as a biomarker of mild traumatic brain injury: findings from THINC and NCAA-DoD CARE Consortium prospective cohorts

C Devoto, R Vorn, S Mithani, TB Meier, C Lai… - Frontiers in …, 2023 - frontiersin.org
Objective The aim of this study was to investigate phosphorylated tau (p-tau181) protein in
plasma in a cohort of mild traumatic brain injury (mTBI) patients and a cohort of concussed …

[HTML][HTML] Concussion-related biomarker variations in retired rugby players and implications for neurodegenerative disease risk: the UK Rugby Health Study

N Alanazi, M Fitzgerald, P Hume, S Hellewell… - International journal of …, 2024 - mdpi.com
The health and well-being of retired rugby union and league players, particularly regarding
the long-term effects of concussions, are of major concern. Concussion has been identified …

Characterizing factors influencing baseline plasma biomarkers for sport-related concussion in adolescents

JB Tabor, LC Penner, JG Cooper, M Ghodsi… - Journal of …, 2023 - liebertpub.com
Developing objective measures to diagnose sport-related concussion (SRC) is a top priority,
particularly in the pediatric context, given the vulnerability of the developing brain. While …

Functional connectivity changes in neurodegenerative biomarker-positive athletes with repeated concussions

I Garcia-Cordero, A Vasilevskaya, F Taghdiri… - Journal of …, 2024 - Springer
Multimodal biomarkers may identify former contact sports athletes with repeated
concussions and at risk for dementia. Our study aims to investigate whether biomarker …

Use of biostatistical models to manage replicate error in concussion biomarker research

JB Tabor, JM Galarneau, LC Penner… - JAMA network …, 2023 - jamanetwork.com
Importance Advancing research on fluid biomarkers associated with sport-related
concussion (SRC) highlights the importance of detecting low concentrations using …

18F-Flortaucipir (AV1451) imaging identifies grey matter atrophy in retired athletes

A Vasilevskaya, C Anastassiadis, S Thapa… - Journal of …, 2024 - Springer
Background The long-term consequences of concussions may include pathological
neurodegeneration as seen in Alzheimer's disease (AD) and chronic traumatic …

Examination of plasma biomarkers of amyloid, tau, neurodegeneration, and neuroinflammation in former elite American football players

AE Miner, JR Groh, Y Tripodis, CH Adler… - Alzheimer's & …, 2024 - Wiley Online Library
INTRODUCTION Blood‐based biomarkers offer a promising approach for the detection of
neuropathologies from repetitive head impacts (RHI). We evaluated plasma biomarkers of …

[PDF][PDF] Plasma Biomarkers Associated with Sport-Related Concussion in Adolescents: Age and Sex Matter

JB Tabor - 2023 - prism.ucalgary.ca
Adolescent sport-related concussion (SRC) is a growing public health concern. Relative to
adult SRC, there exists a large gap in the literature concerning adolescents, with few studies …