Emerging marine biotoxins in European waters: Potential risks and analytical challenges

P Otero, M Silva - Marine Drugs, 2022 - mdpi.com
Harmful algal blooms pose a challenge regarding food safety due to their erratic nature and
forming circumstances which are yet to be disclosed. The best strategy to protect human …

Application of marine natural products against Alzheimer's disease: past, present and future

D Hu, Y Jin, X Hou, Y Zhu, D Chen, J Tai, Q Chen… - Marine Drugs, 2023 - mdpi.com
Alzheimer's disease (AD), a neurodegenerative disease, is one of the most intractable
illnesses which affects the elderly. Clinically manifested as various impairments in memory …

Termination of a toxic Alexandrium bloom with hydrogen peroxide

A Burson, HCP Matthijs, W de Bruijne, R Talens… - Harmful Algae, 2014 - Elsevier
The dinoflagellate Alexandrium ostenfeldii is a well-known harmful algal species that can
potentially cause paralytic shellfish poisoning (PSP). Usually A. ostenfeldii occurs in low …

Cyclic imine toxins from dinoflagellates: A growing family of potent antagonists of the nicotinic acetylcholine receptors

J Molgó, P Marchot, R Aráoz, E Benoit… - Journal of …, 2017 - Wiley Online Library
We present an overview of the toxicological profile of the fast‐acting, lipophilic macrocyclic
imine toxins, an emerging family of organic compounds associated with algal blooms …

Bioactives from microalgal dinoflagellates

J Gallardo-Rodríguez, A Sánchez-Mirón… - Biotechnology …, 2012 - Elsevier
Dinoflagellate microalgae are an important source of marine biotoxins. Bioactives from
dinoflagellates are attracting increasing attention because of their impact on the safety of …

Cyclic imines: Chemistry and mechanism of action: A review

A Otero, MJ Chapela, M Atanassova… - Chemical Research …, 2011 - ACS Publications
In recent years, there has been an increase in the production of shellfish and in global
demand for seafood as nutritious and healthy food. Unfortunately, a significant number of …

Pinnatoxins and spirolides in Norwegian blue mussels and seawater

T Rundberget, JAB Aasen, AI Selwood, CO Miles - Toxicon, 2011 - Elsevier
Fast-acting cyclic imines belonging to the pinnatoxin and pteriatoxin group of toxins were
originally identified in shellfish of the genera Pinna and Pteria in Japan, after food poisoning …

Toxicological perspective on climate change: aquatic toxins

LM Botana - Chemical research in toxicology, 2016 - ACS Publications
In recent years, our group and several others have been describing the presence of new, not
previously reported, toxins of high toxicity in vectors that may reach the human food chain …

Differences in the toxin profiles of Alexandrium ostenfeldii (Dinophyceae) strains isolated from different geographic origins: Evidence of paralytic toxin, spirolide, and …

P Salgado, P Riobó, F Rodríguez, JM Franco, I Bravo - Toxicon, 2015 - Elsevier
Among toxin-producing dinoflagellates of the genus Alexandrium, Alexandrium ostenfeldii is
the only species able to produce paralytic shellfish poisoning (PSP) toxins, spirolides (SPXs) …

[HTML][HTML] A-, B-and C-type prymnesins are clade specific compounds and chemotaxonomic markers in Prymnesium parvum

SB Binzer, DK Svenssen, N Daugbjerg… - Harmful Algae, 2019 - Elsevier
Harmful blooms formed by planktonic microalgae (HABs) in both freshwater and coastal
waters regularly lead to severe mortalities of fish and invertebrates causing substantial …