NMR spectroscopy is a powerful experimental technique to study biological systems at the
atomic resolution. However, its intrinsic low sensitivity results in long acquisition times that in …

We show that the trityl electron spin resonance (ESR) features, crucial for an efficient
dynamic nuclear polarization (DNP) process, are sample-composition-dependent. Working …

Metal ions play important structural and functional roles in many biological systems. The
NMR spectroscopic characterization of biomolecules not only had to deal with the need of …

Paramagnetic relaxation enhancement (PRE) is commonly used to speed up spin lattice
relaxation time (T1) for rapid data acquisition in NMR structural studies. Consequently, there …

A previous study of the effect of Gadolinium doping on the dynamic polarization (DNP) of 13
C using trityls showed that the rate at which the polarization builds up is almost independent …

Lipid-nanodiscs have been shown to be an exciting innovation as a membrane-mimicking
system for studies on membrane proteins by a variety of biophysical techniques, including …

The spin dynamics of dissolution DNP samples consisting of 4.5 M [13 C] urea in a mixture
of (1/1) Vol glycerol/water using 4-Oxo-TEMPO as a radical was investigated. We analyzed …

Dynamic nuclear polarization (DNP) via the dissolution method is one of the most successful
methods for alleviating the inherently low Boltzmann-dictated sensitivity in nuclear magnetic …

Liquid-state nuclear magnetic resonance (NMR) signals can be greatly enhanced by several
thousand-fold via the dissolution-dynamic nuclear polarization (DNP) method. The …

Dissolution dynamic nuclear polarization was introduced in 2003 as a method for producing
hyperpolarized 13C solutions suitable for metabolic imaging. The signal to noise ratio for the …