Astrocytic transcriptional and epigenetic mechanisms of drug addiction

LM Holt, EJ Nestler - Journal of Neural Transmission, 2024 - Springer
Addiction is a leading cause of disease burden worldwide and remains a challenge in
current neuroscience research. Drug-induced lasting changes in gene expression are …

Astrocytes in fragile X syndrome

K Talvio, ML Castrén - Frontiers in Cellular Neuroscience, 2024 - frontiersin.org
Astrocytes have an important role in neuronal maturation and synapse function in the brain.
The interplay between astrocytes and neurons is found to be altered in many …

Rescue of sharp wave-ripples and prevention of network hyperexcitability in the ventral but not the dorsal hippocampus of a rat model of fragile X syndrome

LJ Leontiadis, G Trompoukis, G Tsotsokou… - Frontiers in cellular …, 2023 - frontiersin.org
Fragile X syndrome (FXS) is a genetic neurodevelopmental disorder characterized by
intellectual disability and is related to autism. FXS is caused by mutations of the fragile X …

[HTML][HTML] Reprint of: Fibrinolytic and Non-fibrinolytic Roles of Tissue-type Plasminogen Activator in the Ischemic Brain

M Yepes - Neuroscience, 2024 - Elsevier
The neurovascular unit (NVU) is assembled by endothelial cells (ECs) and pericytes, and
encased by a basement membrane (BM) surveilled by microglia and surrounded by …

Ethanol-induced transcriptional and translational changes in Aldh1l1-Egfp/Rpl10a cortical astrocyte cultures

JG Hashimoto, X Zhang, M Guizzetti - Frontiers in Neuroscience, 2023 - frontiersin.org
The role astrocytes play in brain development and function has garnered greater attention
as the diversity of roles they are involved in has become apparent. We have previously …

[HTML][HTML] RNA sequencing reveals transcriptomic changes in PC-12 cells following plasminogen activator, tissue type overexpression

Y Mao, C Fang, J Zhao, X Huang, W He… - Translational …, 2024 - pmc.ncbi.nlm.nih.gov
Background Pheochromocytoma and paraganglioma, collectively known as PPGL, are
categorized as neuroendocrine tumors with the potential for malignancy. Plasminogen …

Astrocyte extracellular matrix modulates neuronal dendritic development

JG Hashimoto, N Margolies, X Zhang, J Karpf… - …, 2024 - pmc.ncbi.nlm.nih.gov
Major developmental events occurring in the hippocampus during the third trimester of
human gestation and neonatally in altricial rodents include rapid and synchronized dendritic …