Recent advances in neuropeptide signaling in Drosophila, from genes to physiology and behavior

DR Nässel, M Zandawala - Progress in neurobiology, 2019 - Elsevier
This review focuses on neuropeptides and peptide hormones, the largest and most diverse
class of neuroactive substances, known in Drosophila and other animals to play roles in …

A journey into the world of insect lipid metabolism

U Toprak, D Hegedus, C Doğan… - Archives of insect …, 2020 - Wiley Online Library
Lipid metabolism is fundamental to life. In insects, it is critical, during reproduction, flight,
starvation, and diapause. The coordination center for insect lipid metabolism is the fat body …

Metabolism and growth adaptation to environmental conditions in Drosophila

T Koyama, MJ Texada, KA Halberg… - Cellular and Molecular Life …, 2020 - Springer
Organisms adapt to changing environments by adjusting their development, metabolism,
and behavior to improve their chances of survival and reproduction. To achieve such …

The neuropeptide corazonin controls social behavior and caste identity in ants

J Gospocic, EJ Shields, KM Glastad, Y Lin, CA Penick… - Cell, 2017 - cell.com
Social insects are emerging models to study how gene regulation affects behavior because
their colonies comprise individuals with the same genomes but greatly different behavioral …

Endocrine cybernetics: neuropeptides as molecular switches in behavioural decisions

DR Nässel, M Zandawala - Open Biology, 2022 - royalsocietypublishing.org
Plasticity in animal behaviour relies on the ability to integrate external and internal cues from
the changing environment and hence modulate activity in synaptic circuits of the brain. This …

Neurotransmitter classification from electron microscopy images at synaptic sites in Drosophila melanogaster

N Eckstein, AS Bates, A Champion, M Du, Y Yin… - Cell, 2024 - cell.com
High-resolution electron microscopy of nervous systems has enabled the reconstruction of
synaptic connectomes. However, we do not know the synaptic sign for each connection (ie …

The role of peptide hormones in insect lipid metabolism

U Toprak - Frontiers in Physiology, 2020 - frontiersin.org
Lipids are the primary storage molecules and an essential source of energy in insects during
reproduction, prolonged periods of flight, starvation, and diapause. The coordination center …

Hormonal axes in Drosophila: regulation of hormone release and multiplicity of actions

DR Nässel, M Zandawala - Cell and tissue research, 2020 - Springer
Hormones regulate development, as well as many vital processes in the daily life of an
animal. Many of these hormones are peptides that act at a higher hierarchical level in the …

Neural basis of hunger-driven behaviour in Drosophila

S Lin, B Senapati, CH Tsao - Open biology, 2019 - royalsocietypublishing.org
Hunger is a motivational state that drives eating and food-seeking behaviour. In a
psychological sense, hunger sets the goal that guides an animal in the pursuit of food. The …

[HTML][HTML] Impact of high-fat diet on lifespan, metabolism, fecundity and behavioral senescence in Drosophila

S Liao, M Amcoff, DR Nässel - Insect biochemistry and molecular biology, 2021 - Elsevier
Excess consumption of high-fat diet (HFD) is likely to result in obesity and increases the
predisposition to associated health disorders. Drosophila melanogaster has emerged as an …