High-mobility group box 1 and its related receptors: potential therapeutic targets for contrast-induced acute kidney injury
C Mo, Q Huang, L Li, Y Long, Y Shi, Z Lu, N Wu… - … Urology and Nephrology, 2024 - Springer
Percutaneous coronary intervention (PCI) is a crucial diagnostic and therapeutic approach
for coronary heart disease. Contrast agents' exposure during PCI is associated with a risk of …
for coronary heart disease. Contrast agents' exposure during PCI is associated with a risk of …
Concomitant inhibition of TLR-4 and SGLT2 by phloretin and empagliflozin prevents diabetes-associated ischemic acute kidney injury
Toll-like receptor-4 (TLR4) and sodium-glucose co-transporter 2 (SGLT2) signaling is
involved in the pathogenesis of diabetes-associated kidney diseases. The purpose of this …
involved in the pathogenesis of diabetes-associated kidney diseases. The purpose of this …
Phloretin as an add-on therapy to losartan attenuates diabetes-induced AKI in rats: a potential therapeutic approach targeting TLR4-induced inflammation
Abstract Aim Targeting Toll-like receptor 4 (TLR4) and Angiotensin II type 1 receptor (AT1R)
could provide renoprotection during acute kidney injury (AKI) mainly by regulating …
could provide renoprotection during acute kidney injury (AKI) mainly by regulating …
SGLT2 Inhibitor Canagliflozin Alleviates High Glucose-Induced Inflammatory Toxicity in BV-2 Microglia
CT Lee, KD Lin, CF Hsieh, JY Wang - Biomedicines, 2023 - mdpi.com
Patients with diabetes mellitus can experience hyperglycemia, which affects brain function
and produces cognitive impairment or neurodegeneration. Neuroinflammation is an …
and produces cognitive impairment or neurodegeneration. Neuroinflammation is an …
Bioinformatics-based analysis of core genes and pathway enrichment in early diabetic nephropathy
Y Han, X Liu, J Shang, N Li, C Zhang, Y Li… - Cellular and Molecular …, 2023 - cellmolbiol.org
Diabetic nephropathy (DN) is the main cause of end-stage renal disease (ESRD).
Bioinformatics technology was adopted to screen and analyze the core genes of early DN to …
Bioinformatics technology was adopted to screen and analyze the core genes of early DN to …
Network pharmacology combined with molecular docking and dynamics to assess the synergism of esculetin and phloretin against acute kidney injury-diabetes …
Acute kidney injury (AKI) is a global health concern with high incidence and mortality, where
diabetes further worsens the condition. The available treatment options are not uniformly …
diabetes further worsens the condition. The available treatment options are not uniformly …