Acute kidney injury (AKI) following platinum-based chemotherapeutics is a frequently
reported serious side-effect. However, there are no approved biomarkers that can properly …

Immune response, proliferation, migration and angiogenesis are juts a few of cellular events
that are regulated by transforming growth factor-β (TGF-β) in cells. A number of studies have …

Wound healing remains a challenge worldwide, and an ideal wound dressing that promotes
healing is urgently needed. In this study, we developed a thermosensitive injectable …

Nephrotoxicity of oxyfluorfen to vertebrates remains unclear despite its wide use as a
herbicide. In order to further study its nephrotoxicity and its underlying mechanism, we used …

Sirtuin 1 (Sirt1) is an essential modulator of cellular metabolism and has pleiotropic effects. It
was recently reported that Sirt1 overexpression in kidney tubule ameliorates cisplatin …

Melatonin is well known to modulate the sleep–wake cycle. Accumulating evidence
suggests that melatonin also has favorable effects such as anti-oxidant and anti …

Background: the nephrotoxicity of methotrexate (MTX) is observed in high-dose therapy.
Moreover, low-dose MTX therapy for rheumatic diseases is debatable and claimed to cause …

Saving the ovarian function of premature ovarian failure (POF) patients undergoing
chemotherapy is an important problem in the field of reproductive medicine. At present …

Aims This study was designed to evaluate the protective and therapeutic efficacy of platelet-
rich plasma (PRP) against testicular degeneration and germ cell apoptosis after induced …

Aims As a source of growth factors and with its cytoprotective properties, platelet-rich plasma
(PRP) received considerable attention in regenerative medicine. Thus, this study was …