Molecular allergology and its impact in specific allergy diagnosis and therapy
Progressive knowledge of allergenic structures resulted in a broad availability of allergenic
molecules for diagnosis. Component‐resolved diagnosis allowed a better understanding of …
molecules for diagnosis. Component‐resolved diagnosis allowed a better understanding of …
Immune-cell-derived exosomes for cancer therapy
Exosomes are a type of extracellular vesicles secreted by cells in normal or pathological
conditions for cell–cell communication. With immunomodulatory characteristics and potential …
conditions for cell–cell communication. With immunomodulatory characteristics and potential …
Tolerance mechanisms in allergen immunotherapy
Tolerance mechanisms in allergen immunotherapy : Current Opinion in Allergy and Clinical
Immunology Tolerance mechanisms in allergen immunotherapy : Current Opinion in Allergy …
Immunology Tolerance mechanisms in allergen immunotherapy : Current Opinion in Allergy …
Modification of immune cell-derived exosomes for enhanced cancer immunotherapy: current advances and therapeutic applications
Cancer immunotherapy has revolutionized the approach to cancer treatment of malignant
tumors by harnessing the body's immune system to selectively target cancer cells. Despite …
tumors by harnessing the body's immune system to selectively target cancer cells. Despite …
Antibody-mediated regulation of basophils: emerging views and clinical implications
An increasing number of human diseases, including allergies, infections, inflammation, and
cancer, involve roles for basophils. Traditionally viewed as the rarest leukocytes that are …
cancer, involve roles for basophils. Traditionally viewed as the rarest leukocytes that are …
Tolerance mechanisms of AIT
W van de Veen, M Akdis - Allergy, 2020 - zora.uzh.ch
Allergen immunotherapy (AIT) is the only curative treatment for allergic diseases. It induces
immune tolerance together with the reduction of the symptoms of asthma and allergic rhinitis …
immune tolerance together with the reduction of the symptoms of asthma and allergic rhinitis …
Regulatory B cells control airway hyperreactivity and lung remodeling in a murine asthma model
A Habener, C Happle, R Grychtol, J Skuljec… - Journal of Allergy and …, 2021 - Elsevier
Background Asthma is a widespread, multifactorial chronic airway disease. The influence of
regulatory B cells on airway hyperreactivity (AHR) and remodeling in asthma is poorly …
regulatory B cells on airway hyperreactivity (AHR) and remodeling in asthma is poorly …
Stimulation of naïve b cells with a fusion protein consisting of FlaA and bet v 1 induces regulatory b cells ex vivo
Background The experimental fusion protein rFlaA: Betv1 was shown to efficiently suppress
allergen‐specific sensitization in mice. However, the detailed mechanism of rFlaA: Betv1 …
allergen‐specific sensitization in mice. However, the detailed mechanism of rFlaA: Betv1 …
In vivo Induction of Functional Inhibitory IgG Antibodies by a Hypoallergenic Bet v 1 Variant
L Aglas, A Bethanis, P Chrusciel, F Stolz… - Frontiers in …, 2020 - frontiersin.org
Allergic sensitization to the major allergen Bet v 1 represents the dominating factor inducing
a vast variety of allergic symptoms in birch pollen allergic patients worldwide, including the …
a vast variety of allergic symptoms in birch pollen allergic patients worldwide, including the …
Allergen immunotherapy for pediatric asthma: current evidence and knowledge gaps
Allergen immunotherapy is overall effective for the treatment of asthma in children, but a
class-effect should not be claimed, rather the efficacy of each single product. According to …
class-effect should not be claimed, rather the efficacy of each single product. According to …