Discovery of novel pyrazole and pyrazolo[1,5‐a]pyrimidine derivatives as cyclooxygenase inhibitors (COX‐1 and COX‐2) using molecular modeling simulation
Searching for effective and selective anti‐inflammatory agents, our study involved designing
and synthesizing new pyrazole and pyrazolo [1, 5‐a] pyrimidine derivatives 4–11. The …
and synthesizing new pyrazole and pyrazolo [1, 5‐a] pyrimidine derivatives 4–11. The …
Development of novel pyrazole, imidazo [1, 2-b] pyrazole, and pyrazolo [1, 5-a] pyrimidine derivatives as a new class of COX-2 inhibitors with immunomodulatory …
Searching for new compounds with anti-inflammatory properties is a significant target since
inflammation is a major cause of pain. A series of pyrazole, imidazopyrazolone, and …
inflammation is a major cause of pain. A series of pyrazole, imidazopyrazolone, and …
A review on multipurpose potential of bioactive heterocycle quinoxaline
In last few decades, nitrogen‐containing heterocycles have maintained their status as an
important core of FDA‐approved drugs and medicinally active compounds. Quinoxaline is …
important core of FDA‐approved drugs and medicinally active compounds. Quinoxaline is …
Recent methods for the synthesis of quinoxaline derivatives and their biological activities
TA Farghaly, RM Alqurashi, GS Masaret… - Mini Reviews in …, 2024 - ingentaconnect.com
Quinoxaline derivatives have been incorporated into numerous marketed drugs used for the
treatment of various diseases. Examples include glecaprevir (Mavyret), voxilaprevir (Vosevi) …
treatment of various diseases. Examples include glecaprevir (Mavyret), voxilaprevir (Vosevi) …
Electrochemical Detection of 4-Nitrophenol Using a Novel SrTiO3/Ag/rGO Composite
A M. Visagamani, M Harb, K Kaviyarasu… - ACS …, 2023 - ACS Publications
In this study, an eco-friendly strategy was used to prepare a novel SrTiO3/Ag/rGO composite.
A SrTiO3/Ag/rGO composite-modified screen-printed carbon electrode (SPCE) was applied …
A SrTiO3/Ag/rGO composite-modified screen-printed carbon electrode (SPCE) was applied …
Synthesis of thiophene derivatives: Substituent effect, antioxidant activity, cyclic voltammetry, molecular docking, DFT, and TD-DFT calculations
N Uludag, G Serdaroğlu, P Sugumar… - Journal of Molecular …, 2022 - Elsevier
Abstract The efficient pathway 6-methyl-4, 5, 6, 7-tetrahydrobenzo [b] thiophene-3-
carboxylate derivatives have been synthesized. Due to the promising biochemical reactivity …
carboxylate derivatives have been synthesized. Due to the promising biochemical reactivity …
Synthesis, spectral characterization, DFT-computational analyses on Novel 4-nitrobenzenaminium benzenesulfonate (4NBASA) crystal
Abstract Novel 4-nitrobenzenaminium benzenesulfonate (4NBASA) was synthesized and
evaluated using Fourier Transform Infrared (FTIR), 1H and 13C Nuclear Magnetic …
evaluated using Fourier Transform Infrared (FTIR), 1H and 13C Nuclear Magnetic …
Synthesis, spectral characterizations, vibrational spectroscopy, DFT-computations, antibacterial, antioxidant, and molecular docking studies of the novel (Z)-2-(5-((10 …
The Synthesized novel compound of (Z)-2-(5-((10-hexyl-10H-phenothiazin-3-yl) methylene)-
4-oxo-2-thioxothiazolidin-3-yl) acetic acid (PTZTZ) was charecterized by nuclear magnetic …
4-oxo-2-thioxothiazolidin-3-yl) acetic acid (PTZTZ) was charecterized by nuclear magnetic …
[HTML][HTML] Quinoxaline derivatives: Recent discoveries and development strategies towards anticancer agents
V Montero, M Montana, M Carré, P Vanelle - European Journal of …, 2024 - Elsevier
Cancer is a leading cause of death and a major health problem worldwide. While many
effective anticancer agents are available, most drugs currently on the market are not specific …
effective anticancer agents are available, most drugs currently on the market are not specific …
Spectroscopic, computational DFT, in vitro, and molecular docking investigations of newly isolated 2, 3, 9, and 10-tetrahydroacridin-3-one from the methanolic extract …
The Gaussian09 program was studied by using the optimized molecular structure with
vibrational frequency assignments of 2, 3, 9, and 10 tetrahydroacridin-3-one (abbreviated as …
vibrational frequency assignments of 2, 3, 9, and 10 tetrahydroacridin-3-one (abbreviated as …