Fatty acid synthase: an emerging target in cancer
CW Fhu, A Ali - Molecules, 2020 - mdpi.com
In recent years, lipid metabolism has garnered significant attention as it provides the
necessary building blocks required to sustain tumor growth and serves as an alternative fuel …
necessary building blocks required to sustain tumor growth and serves as an alternative fuel …
Orchestral role of lipid metabolic reprogramming in T-cell malignancy
The immune function of normal T cells partially depends on the maneuvering of lipid
metabolism through various stages and subsets. Interestingly, T-cell malignancies also …
metabolism through various stages and subsets. Interestingly, T-cell malignancies also …
Shaping of innate immune response by fatty acid metabolite palmitate
HT Tzeng, IT Chyuan, WY Chen - Cells, 2019 - mdpi.com
Innate immune cells monitor invading pathogens and pose the first-line inflammatory
response to coordinate with adaptive immunity for infection removal. Innate immunity also …
response to coordinate with adaptive immunity for infection removal. Innate immunity also …
High-density lipoproteins decrease proinflammatory activity and modulate the innate immune response
NA Taborda, Y Blanquiceth… - Journal of Interferon & …, 2019 - liebertpub.com
Atherosclerosis, a chronic inflammatory disease of the arterial wall, is the leading cause of
cardiac disorders and stroke. The onset and progression of these diseases are linked with …
cardiac disorders and stroke. The onset and progression of these diseases are linked with …
Nimbolide retards T cell lymphoma progression by altering apoptosis, glucose metabolism, pH regulation, and ROS homeostasis
PK Jaiswara, A Kumar - Environmental Toxicology, 2022 - Wiley Online Library
Nimbolide is reported as one of the potential anticancer candidates of the neem tree
(Azadirachta indica A. Juss). The cytotoxic action of nimbolide has been well reported …
(Azadirachta indica A. Juss). The cytotoxic action of nimbolide has been well reported …
[HTML][HTML] Function and regulation of lipid signaling in lymphomagenesis: a novel target in cancer research and therapy
W Guo, X Wang, Y Li, O Bai - Critical Reviews in Oncology/Hematology, 2020 - Elsevier
To survive under the challenging conditions, cancer cells adapt their own metabolic
mechanism (s) to be able steady supplying energy and metabolites for synthesis of new …
mechanism (s) to be able steady supplying energy and metabolites for synthesis of new …
Upregulation of fatty acid synthase in MYC and BCL‑2 double‑expressor lymphoma
X Zhong, Z Liu, Q Luo, J Li, W Zhang… - Oncology …, 2021 - spandidos-publications.com
Diffuse large B‑cell lymphoma (DLBCL) is the most common and heterogeneous lymphoid
malignancy. The subtype with MYC and BCL‑2 double‑expressor lymphoma (DEL) was …
malignancy. The subtype with MYC and BCL‑2 double‑expressor lymphoma (DEL) was …
A random walk-based method to identify candidate genes associated with lymphoma
M Sheng, H Cai, Q Yang, J Li, J Zhang, L Liu - Frontiers in Genetics, 2021 - frontiersin.org
Lymphoma is a serious type of cancer, especially for adolescents and elder adults, although
this malignancy is quite rare compared with other types of cancer. The cause of this …
this malignancy is quite rare compared with other types of cancer. The cause of this …
Compounds and compositions for inhibition of FASN
KW Bair, DR Lancia Jr, H Li, J Loch, W Lu… - US Patent …, 2019 - Google Patents
2018-02-20 Assigned to FORMA THERAPEUTICS, INC. reassignment FORMA
THERAPEUTICS, INC. ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR …
THERAPEUTICS, INC. ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR …
Compounds and compositions for inhibition of FASN
KW Bair, DR Lancia Jr, H Li, J Loch, W Lu… - US Patent …, 2019 - Google Patents
2018-09-24 Assigned to FORMA THERAPEUTICS, INC. reassignment FORMA
THERAPEUTICS, INC. ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR …
THERAPEUTICS, INC. ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR …