The role of the microbiota in infectious diseases
J Libertucci, VB Young - Nature microbiology, 2019 - nature.com
The human body is colonized by a diverse community of microorganisms collectively
referred to as the microbiota. Here, we describe how the human microbiota influences …
referred to as the microbiota. Here, we describe how the human microbiota influences …
Bacterial vaginosis: current diagnostic avenues and future opportunities
A healthy female genital tract harbors a microbiome dominated by lactic acid and hydrogen
peroxide producing bacteria, which provide protection against infections by maintaining a …
peroxide producing bacteria, which provide protection against infections by maintaining a …
The evolving facets of bacterial vaginosis: implications for HIV transmission
Bacterial vaginosis (BV) is a common yet poorly understood vaginal condition that has
become a major focus of HIV transmission and immunology research. Varied terminologies …
become a major focus of HIV transmission and immunology research. Varied terminologies …
Genital inflammation and the risk of HIV acquisition in women
Abstract Background. Women in Africa, especially young women, have very high human
immunodeficiency virus (HIV) incidence rates that cannot be fully explained by behavioral …
immunodeficiency virus (HIV) incidence rates that cannot be fully explained by behavioral …
Linking cervicovaginal immune signatures, HPV and microbiota composition in cervical carcinogenesis in non-Hispanic and Hispanic women
P Łaniewski, D Barnes, A Goulder, H Cui, DJ Roe… - Scientific reports, 2018 - nature.com
While high-risk human papillomavirus (HPV) infection is a well-established risk factor for
cervical cancer, there are likely other factors within the local microenvironment that …
cervical cancer, there are likely other factors within the local microenvironment that …
Influence of Biofilm Formation by Gardnerella vaginalis and Other Anaerobes on Bacterial Vaginosis
Bacterial vaginosis (BV) is the worldwide leading vaginal disorder among women of
reproductive age. BV is characterized by the replacement of beneficial lactobacilli and the …
reproductive age. BV is characterized by the replacement of beneficial lactobacilli and the …
[HTML][HTML] Increased levels of inflammatory cytokines in the female reproductive tract are associated with altered expression of proteases, mucosal barrier proteins, and …
Elevated inflammatory cytokines (EMCs) at mucosal surfaces have been associated with
HIV susceptibility, but the underlying mechanisms remain unclear. We characterized the …
HIV susceptibility, but the underlying mechanisms remain unclear. We characterized the …
Sex differences in HIV infection
EP Scully - Current HIV/AIDS Reports, 2018 - Springer
Abstract Purpose of Review This review will outline the multilevel effects of biological sex on
HIV acquisition, pathogenesis, treatment response, and prospects for cure. Potential …
HIV acquisition, pathogenesis, treatment response, and prospects for cure. Potential …
[HTML][HTML] Vaginal lactic acid elicits an anti-inflammatory response from human cervicovaginal epithelial cells and inhibits production of pro-inflammatory mediators …
AC Hearps, D Tyssen, D Srbinovski, L Bayigga… - Mucosal …, 2017 - Elsevier
Inflammation in the female reproductive tract (FRT) is associated with increased HIV
transmission. Lactobacillus spp. dominate the vaginal microbiota of many women and their …
transmission. Lactobacillus spp. dominate the vaginal microbiota of many women and their …
Association of HPV infection and clearance with cervicovaginal immunology and the vaginal microbiota
B Shannon, TJ Yi, S Perusini, P Gajer, B Ma… - Mucosal …, 2017 - nature.com
Cervical human papillomavirus (HPV) infection may increase HIV risk. Since other genital
infections enhance HIV susceptibility by inducing inflammation, we assessed the impact of …
infections enhance HIV susceptibility by inducing inflammation, we assessed the impact of …