This paper reviews microfluidic technologies with emphasis on applications in the fields of
pharmacy, biology, and tissue engineering. Design and fabrication of microfluidic systems …

Integration of various chemical devices and complex operations onto a microchip, which is
often referred to as a micro total analysis system (μ-TAS) or lab-on-a-chip, creates extremely …

We developed a microfluidic model of microcirculation containing both blood and lymphatic
vessels for examining vascular permeability. The designed microfluidic device harbors …

Living cells are a fascinating demonstration of nature's most intricate and well-coordinated
micromechanical objects. They crawl, spread, contract, and relax—thus performing a …

In this work, we demonstrated that biological cells could be cultured in a continuous-
perfusion glass microchip system for drug screening. We used mouse Col1a1GFP MC-3T3 …

We developed a microfluidic perfusion cell culture chip that provides three different shear
stress strengths and a large cell culture area for the analysis of vascular endothelial …

We describe a simple and efficient fabrication method for generating microfluidic channels
with a circular cross-sectional geometry by exploiting the reflow phenomenon of a thick …

Vascular tissues fabricated in vitro are useful tools for studying blood vessel‐related cellular
physiologies and for constructing relatively large 3D tissues. An efficient strategy for …

We fabricated a three-dimensional multilayered blood vessel model using human cells and
high-strength PEG hydrogel. The hydrogel tube was physically suitable for perfusion culture …

Cell analysis and clinical diagnosis systems are now becoming the largest field of
application for microchip-based analytical systems. Technological advantages include …