Spinal cord injury is a devastating condition in which massive cell death and disruption of
neural circuitry lead to long-term chronic functional impairment and paralysis. In mammals …

Following an injury, axons of both the central nervous system (CNS) and peripheral nervous
system (PNS) degenerate through a coordinated and genetically conserved mechanism …

Gonadotropins play vital roles in the regulation of female reproductive ability and fertility. Our
study aimed to determine the effects of superovulation induced by increasing doses of …

Kinases are essential regulators of a variety of cellular signaling processes, including
neurite formation—a foundational step in neurodevelopment. Aberrant axonal sprouting and …

Although cytokinesis has been intensely studied, the way it is executed during development
is not well understood, despite a long-standing appreciation that various aspects of …

Dysregulated axonal trafficking of mitochondria is linked to neurodegenerative disorders.
We report a high-content screen for small-molecule regulators of the axonal transport of …

Centrosomes control cell motility, polarity and migration that is thought to be mediated by
their microtubule-organizing capacity. Here we demonstrate that WNT signalling drives a …

Abstract Individuals with Alzheimer Disease who develop psychotic symptoms (AD+ P)
experience more rapid cognitive decline and have reduced indices of synaptic integrity …

Little is known about the key molecules that regulate cell division during organogenesis.
Here we determine the role of the cell cycle promoter aurora kinase B (AURKB) during …

The hypothalamic-pituitary-adrenal (HPA) axis is an important component of
neuroendocrine stress regulation and coping behavior. Transcriptome profiles of the …