The global diversity of fungi has been estimated between 2 to 11 million species, of which
only about 155 000 have been named. Most fungi are invisible to the unaided eye, but they …

Monomeric GTPases, which belong to the Ras superfamily, are small proteins involved in
many biological processes. They are fine-tuned regulated by guanine nucleotide exchange …

Morphological changes are critical for the virulence of a range of plant and human fungal
pathogens. Candida albicans is a major human fungal pathogen whose ability to switch …

RAB GTPases are major determinants of membrane identity that have been exploited as
highly specific reporters to study intracellular traffic in vivo. A score of fungal papers have …

SNARE-mediated fusion of endosome-derived transport carriers with the trans-Golgi
network (TGN) depends on the concerted action of two types of tethering factors: long coiled …

Ras-GTPases are nucleotide hydrolases involved in key cellular processes. In fungi, Ras-
GTPases regulate conidiation, development, virulence, and interactions with other fungi or …

Candida albicans is a fungus that is a commensal organism and a member of the normal
human microbiota. It has the ability to transition into an opportunistic invasive pathogen …

Ypts (y east p rotein t ransport s), also called as r as-a ssociated b inding GTPases (Rab),
are the largest group of the small GTPases family, which have been extensively studied in …

Candida albicans is an opportunistic fungal pathogen that colonises the skin as well as
genital and intestinal mucosa of most healthy individuals. The ability of C. albicans to switch …

During symmetry breaking, the highly conserved Rho GTPase Cdc42 becomes stabilized at
a defined site via an amplification process. However, little is known about how a new polarity …