[HTML][HTML] Epstein-Barr virus and systemic autoimmune diseases

G Houen, NH Trier - Frontiers in immunology, 2021 - frontiersin.org
Epstein-Barr Virus (EBV) is an extremely successful human herpes virus, which infects
essentially all human beings at some time during their life span. EBV infection and the …

Nuclear egress

EB Draganova, MK Thorsen, EE Heldwein - Current issues in molecular …, 2021 - mdpi.com
During viral replication, herpesviruses utilize a unique strategy, termed nuclear egress, to
translocate capsids from the nucleus into the cytoplasm. This initial budding step transfers a …

Absence of Epstein-Barr virus in the brain and CSF of patients with multiple sclerosis

SA Sargsyan, AJ Shearer, AM Ritchie, MP Burgoon… - Neurology, 2010 - AAN Enterprises
Objective: Epstein-Barr virus (EBV) is a ubiquitous human herpesvirus that becomes latent
in B-lymphocytes and has been implicated in the pathogenesis of multiple sclerosis (MS) …

Herpes simplex virus type 1 infection induces activation and recruitment of protein kinase C to the nuclear membrane and increased phosphorylation of lamin B

R Park, JD Baines - Journal of virology, 2006 - Am Soc Microbiol
We report that herpes simplex virus type 1 (HSV-1) infection leads to the recruitment of
protein kinase C (PKC) to the nuclear rim. In HEp-2 cells, PKC recruitment to the nuclear rim …

Vesicle formation from the nuclear membrane is induced by coexpression of two conserved herpesvirus proteins

BG Klupp, H Granzow, W Fuchs… - Proceedings of the …, 2007 - National Acad Sciences
Although the nuclear envelope is a dynamic structure that disassembles and reforms during
mitosis, the formation of membranous vesicles derived from the nuclear envelope has not …

The ESCRT machinery is recruited by the viral BFRF1 protein to the nucleus-associated membrane for the maturation of Epstein-Barr Virus

CP Lee, PT Liu, HN Kung, MT Su, HH Chua, YH Chang… - 2012 - journals.plos.org
The cellular endosomal sorting complex required for transport (ESCRT) machinery
participates in membrane scission and cytoplasmic budding of many RNA viruses. Here, we …

Epstein-Barr virus lytic infection promotes activation of Toll-like receptor 8 innate immune response in systemic sclerosis monocytes

A Farina, G Peruzzi, V Lacconi, S Lenna… - Arthritis research & …, 2017 - Springer
Background Monocytes/macrophages are activated in several autoimmune diseases,
including systemic sclerosis (scleroderma; SSc), with increased expression of interferon …

[HTML][HTML] Roles for herpes simplex virus type 1 UL34 and US3 proteins in disrupting the nuclear lamina during herpes simplex virus type 1 egress

SL Bjerke, RJ Roller - Virology, 2006 - Elsevier
Cells infected with wild type HSV-1 showed significant lamin A/C and lamin B
rearrangement, while UL34-null virus-infected cells exhibited few changes in lamin …

Identification and functional evaluation of cellular and viral factors involved in the alteration of nuclear architecture during herpes simplex virus 1 infection

M Simpson-Holley, RC Colgrove, G Nalepa… - Journal of …, 2005 - Am Soc Microbiol
ABSTRACT Herpes simplex virus 1 (HSV-1) replicates in the nucleus of host cells and
radically alters nuclear architecture as part of its replication process. Replication …

Emerin is hyperphosphorylated and redistributed in herpes simplex virus type 1-infected cells in a manner dependent on both UL34 and US3

N Leach, SL Bjerke, DK Christensen… - Journal of …, 2007 - Am Soc Microbiol
Cells infected with wild-type herpes simplex virus type 1 (HSV-1) show disruption of the
organization of the nuclear lamina that underlies the nuclear envelope. This disruption is …