During viral replication, herpesviruses utilize a unique strategy, termed nuclear egress, to translocate capsids from the nucleus into the cytoplasm. This initial budding step transfers a …
SA Sargsyan, AJ Shearer, AM Ritchie, MP Burgoon… - Neurology, 2010 - AAN Enterprises
Objective: Epstein-Barr virus (EBV) is a ubiquitous human herpesvirus that becomes latent in B-lymphocytes and has been implicated in the pathogenesis of multiple sclerosis (MS) …
R Park, JD Baines - Journal of virology, 2006 - Am Soc Microbiol
We report that herpes simplex virus type 1 (HSV-1) infection leads to the recruitment of protein kinase C (PKC) to the nuclear rim. In HEp-2 cells, PKC recruitment to the nuclear rim …
BG Klupp, H Granzow, W Fuchs… - Proceedings of the …, 2007 - National Acad Sciences
Although the nuclear envelope is a dynamic structure that disassembles and reforms during mitosis, the formation of membranous vesicles derived from the nuclear envelope has not …
The cellular endosomal sorting complex required for transport (ESCRT) machinery participates in membrane scission and cytoplasmic budding of many RNA viruses. Here, we …
A Farina, G Peruzzi, V Lacconi, S Lenna… - Arthritis research & …, 2017 - Springer
Background Monocytes/macrophages are activated in several autoimmune diseases, including systemic sclerosis (scleroderma; SSc), with increased expression of interferon …
Cells infected with wild type HSV-1 showed significant lamin A/C and lamin B rearrangement, while UL34-null virus-infected cells exhibited few changes in lamin …
M Simpson-Holley, RC Colgrove, G Nalepa… - Journal of …, 2005 - Am Soc Microbiol
ABSTRACT Herpes simplex virus 1 (HSV-1) replicates in the nucleus of host cells and radically alters nuclear architecture as part of its replication process. Replication …
N Leach, SL Bjerke, DK Christensen… - Journal of …, 2007 - Am Soc Microbiol
Cells infected with wild-type herpes simplex virus type 1 (HSV-1) show disruption of the organization of the nuclear lamina that underlies the nuclear envelope. This disruption is …