[HTML][HTML] The anatomy of pain and suffering in the brain and its clinical implications
Pain is an unpleasant sensory and emotional experience associated with actual or potential
tissue damage. Chronic pain, with a prevalence of 20–30% is the major cause of human …
tissue damage. Chronic pain, with a prevalence of 20–30% is the major cause of human …
[HTML][HTML] Role of the prefrontal cortex in pain processing
WY Ong, CS Stohler, DR Herr - Molecular neurobiology, 2019 - Springer
The prefrontal cortex (PFC) is not only important in executive functions, but also pain
processing. The latter is dependent on its connections to other areas of the cerebral …
processing. The latter is dependent on its connections to other areas of the cerebral …
[HTML][HTML] Cellular circuits in the brain and their modulation in acute and chronic pain
Chronic, pathological pain remains a global health problem and a challenge to basic and
clinical sciences. A major obstacle to preventing, treating, or reverting chronic pain has been …
clinical sciences. A major obstacle to preventing, treating, or reverting chronic pain has been …
[HTML][HTML] Pain and the triple network model
Acute pain is a physiological response that causes an unpleasant sensory and emotional
experience in the presence of actual or potential tissue injury. Anatomically and …
experience in the presence of actual or potential tissue injury. Anatomically and …
A Guide to the Metabolic Pathways and Function of Metabolites Observed in Human Brain 1H Magnetic Resonance Spectra
CD Rae - Neurochemical research, 2014 - Springer
The current knowledge of the normal biochemistry of compounds that give rise to
resonances in human brain proton magnetic resonance spectra measureable at readily …
resonances in human brain proton magnetic resonance spectra measureable at readily …
[HTML][HTML] Brain GABA and glutamate levels across pain conditions: a systematic literature review and meta-analysis of 1H-MRS studies using the MRS-Q quality …
Background A proposed mechanism of chronic pain is dysregulation between the main
inhibitory (GABA) and excitatory (glutamate) neurometabolites of the central nervous system …
inhibitory (GABA) and excitatory (glutamate) neurometabolites of the central nervous system …
Frontostriatal gating of tinnitus and chronic pain
JP Rauschecker, ES May, A Maudoux… - Trends in cognitive …, 2015 - cell.com
Tinnitus and chronic pain are sensory–perceptual disorders associated with negative affect
and high impact on well-being and behavior. It is now becoming increasingly clear that …
and high impact on well-being and behavior. It is now becoming increasingly clear that …
[HTML][HTML] Distinct thalamocortical network dynamics are associated with the pathophysiology of chronic low back pain
Thalamocortical dysrhythmia is a key pathology of chronic neuropathic pain, but few studies
have investigated thalamocortical networks in chronic low back pain (cLBP) given its non …
have investigated thalamocortical networks in chronic low back pain (cLBP) given its non …
Methods and strategies of tDCS for the treatment of pain: current status and future directions
K Pacheco-Barrios, A Cardenas-Rojas… - Expert review of …, 2020 - Taylor & Francis
Introduction Transcranial direct current stimulation (tDCS) is a noninvasive neuromodulation
technique that has been widely studied for the treatment of chronic pain. It is considered a …
technique that has been widely studied for the treatment of chronic pain. It is considered a …
[HTML][HTML] Disruption of default mode network dynamics in acute and chronic pain states
It has been proposed that pain competes with other attention-demanding stimuli for cognitive
resources, and many chronic pain patients display significant attention and mental flexibility …
resources, and many chronic pain patients display significant attention and mental flexibility …