Clinical application and detection techniques of liquid biopsy in gastric cancer

S Ma, M Zhou, Y Xu, X Gu, M Zou, G Abudushalamu… - Molecular Cancer, 2023 - Springer
Gastric cancer (GC) is one of the most common tumors worldwide and the leading cause of
tumor-related mortality. Endoscopy and serological tumor marker testing are currently the …

Systems biology of cisplatin resistance: past, present and future

L Galluzzi, I Vitale, J Michels, C Brenner… - Cell death & …, 2014 - nature.com
The platinum derivative cis-diamminedichloroplatinum (II), best known as cisplatin, is
currently employed for the clinical management of patients affected by testicular, ovarian …

based strip for ultrasensitive detection of OSCC-associated salivary microRNA via CRISPR/Cas12a coupling with IS-primer amplification reaction

M Chen, R Luo, S Li, H Li, Y Qin, D Zhou… - Analytical …, 2020 - ACS Publications
As the most common malignancy in humans, oral squamous cell carcinoma (OSCC) not only
harms the people's health but also undermines their confidence after facial surgery. Early …

[HTML][HTML] The serum miR-21 level serves as a predictor for the chemosensitivity of advanced pancreatic cancer, and miR-21 expression confers chemoresistance by …

P Wang, L Zhuang, J Zhang, J Fan, J Luo, H Chen… - Molecular …, 2013 - Elsevier
miR-21 expression in cancer tissue has been reported to be associated with the clinical
outcome and activity of gemcitabine in pancreatic cancer. However, resection is possible in …

miR-204 targets Bcl-2 expression and enhances responsiveness of gastric cancer

A Sacconi, F Biagioni, V Canu, F Mori… - Cell death & …, 2012 - nature.com
Micro RNAs (miRs) are small non-coding RNAs aberrantly expressed in human tumors.
Here, we aim to identify miRs whose deregulated expression leads to the activation of …

miR-508-5p regulates multidrug resistance of gastric cancer by targeting ABCB1 and ZNRD1

Y Shang, Z Zhang, Z Liu, B Feng, G Ren, K Li, L Zhou… - Oncogene, 2014 - nature.com
Multidrug resistance (MDR) is usually correlated with the poor prognosis of gastric cancer. In
this study, we revealed a total of 11 microRNAs (miRNA) that regulated MDR of gastric …

Caspase-9 as a therapeutic target for treating cancer

B Kim, SK Srivastava, SH Kim - Expert Opinion on Therapeutic …, 2015 - Taylor & Francis
Introduction: Caspase-9 is the apoptotic initiator protease of the intrinsic or mitochondrial
apoptotic pathway, which is activated at multi-protein activation platforms. Its activation is …

[HTML][HTML] Circulating microRNAs and long non-coding RNAs in gastric cancer diagnosis: an update and review

YK Huang, JC Yu - World journal of gastroenterology: WJG, 2015 - ncbi.nlm.nih.gov
Gastric cancer (GC) is the fourth most common cancer and the third leading cause of cancer
mortality worldwide. MicroRNAs (miRNAs) and long non-coding RNAs (lncRNAs) are the …

Potential diagnostic, prognostic and therapeutic targets of microRNAs in human gastric cancer

MM Tsai, CS Wang, CY Tsai, HW Huang… - International journal of …, 2016 - mdpi.com
Human gastric cancer (GC) is characterized by a high incidence and mortality rate, largely
because it is normally not identified until a relatively advanced stage owing to a lack of early …

Circulating microRNAs as potential diagnostic biomarkers and therapeutic targets in gastric cancer: current status and future perspectives

H Mirzaei, S Khataminfar… - Current medicinal …, 2016 - ingentaconnect.com
Gastric cancer is among the leading causes of cancer related death worldwide. Patients with
gastric cancer are typically asymptomatic, and diagnosed at late stages, supporting the need …