[HTML][HTML] A bird's eye view on a therapeutically 'wonder molecule': Berberine

P Patel - Phytomedicine Plus, 2021 - Elsevier
Berberine is a quaternary ammonium salt and naturally occurring benzylisoquinoline
alkaloid, present in numerous medicinal herbs' roots and stem bark as an active constituent …

Berberine—a promising therapeutic approach to polycystic ovary syndrome in infertile/pregnant women

OM Ionescu, F Frincu, A Mehedintu, M Plotogea… - Life, 2023 - mdpi.com
Polycystic ovary syndrome (PCOS) is a disorder with an unknown etiology that features a
wide range of endocrine and metabolic abnormalities that hamper fertility. PCOS women …

[HTML][HTML] Antibacterial activity and antifungal activity of monomeric alkaloids

AM Thawabteh, AW Ghanem, S AbuMadi, D Thaher… - Toxins, 2024 - mdpi.com
Scientists are becoming alarmed by the rise in drug-resistant bacterial and fungal strains,
which makes it more costly, time-consuming, and difficult to create new antimicrobials from …

Blocking HMGB1/RAGE signaling by berberine alleviates A1 astrocyte and attenuates sepsis-associated encephalopathy

J Shi, H Xu, MJ Cavagnaro, X Li, J Fang - Frontiers in Pharmacology, 2021 - frontiersin.org
As a life-threatening multiple organ dysfunction attributable to maladjusted host immune
responses to infection, sepsis is usually the common pathway to serious prognosis and …

Recent Applications of Protoberberines as Privileged Starting Materials for the Development of Novel Broad-Spectrum Antiviral Agents: A Concise Review (2017 …

M Valipour, Z Zakeri Khatir, E Abdollahi… - ACS Pharmacology & …, 2023 - ACS Publications
Berberine is a well-known phytochemical with significant antiviral activity against a wide
range of viruses. Due to having a unique backbone consisting of four interconnected rings, it …

Pharmacology of Berberine and its Metabolites, is it the natures Ozempic or Imatinib?

NK Singh, M Dhanasekaran, AHS Kumar - bioRxiv, 2023 - biorxiv.org
Background: Berberine, which is a naturally occurring alkaloid is widely explored for several
health benefits including for weight management and metabolic disorders. The major …

The Possible Synergistic Pharmacological Effect of an Oral Berberine (BBR) and Curcumin (CUR) Complementary Therapy Alleviates Symptoms of Irritable Bowel …

U Wade, DA Pascual-Figal, F Rabbani, M Ernst… - Nutrients, 2024 - mdpi.com
Irritable bowel syndrome (IBS) is a prevalent chronic functional gastrointestinal disorder,
characterised by recurrent abdominal discomfort and altered bowel movements. IBS cause a …

[HTML][HTML] Perspectives on Berberine and the Regulation of Gut Microbiota: As an Anti-Inflammatory Agent

QV Jael Teresa de Jesús, JC Gálvez-Ruíz… - Pharmaceuticals, 2025 - mdpi.com
Berberine is a promising agent for modulating the intestinal microbiota, playing a crucial role
in human health homeostasis. This natural compound promotes the growth of beneficial …

Pharmaceutical Analysis of Berberine: An Update

PS Bobade, SB Ganorkar, PN Baviskar… - Separation & …, 2024 - Taylor & Francis
The benzylisoquinoline alkaloid Berberine (BER) is a crucial phytopharmaceutical. The
present review focuses on the precise analytical BER profile. The accurate BER estimation …

C19 Benzylisoquinoline Alkaloid with Unprecedented Architecture from Hypecoum erectum

HL Yuan, YL Zhao, K Hu, YJ He… - The Journal of Organic …, 2021 - ACS Publications
Hyperectumine (1), the first C19 benzylisoquinoline alkaloid with a complicated ring system,
was isolated from Hypecoum erectum and structurally characterized. Its biosynthetic origin …