Therapeutic nanoparticles and their targeted delivery applications

AA Yetisgin, S Cetinel, M Zuvin, A Kosar, O Kutlu - Molecules, 2020 - mdpi.com
Nanotechnology offers many advantages in various fields of science. In this regard,
nanoparticles are the essential building blocks of nanotechnology. Recent advances in …

[HTML][HTML] Neuroprotective and antioxidant effect of Ginkgo biloba extract against AD and other neurological disorders

SK Singh, S Srivastav, RJ Castellani… - …, 2019 - Elsevier
Alzheimer's disease (AD) is the most common progressive human neurodegenerative
disorder affecting elderly population worldwide. Hence, prevention of AD has been a priority …

The epigenetics of aging and neurodegeneration

R Lardenoije, A Iatrou, G Kenis, K Kompotis… - Progress in …, 2015 - Elsevier
Epigenetics is a quickly growing field encompassing mechanisms regulating gene
expression that do not involve changes in the genotype. Epigenetics is of increasing …

Biomarkers for Alzheimer's disease: academic, industry and regulatory perspectives

H Hampel, R Frank, K Broich, SJ Teipel… - Nature reviews Drug …, 2010 - nature.com
Advances in therapeutic strategies for Alzheimer's disease that lead to even small delays in
onset and progression of the condition would significantly reduce the global burden of the …

New pharmacological strategies for treatment of Alzheimer's disease: focus on disease modifying drugs

S Salomone, F Caraci, GM Leggio… - British journal of …, 2012 - Wiley Online Library
Current approved drug treatments for Alzheimer disease (AD) include cholinesterase
inhibitors (donepezil, rivastigmine, galantamine) and the NMDA receptor antagonist …

Efficacy and safety of a liposome-based vaccine against protein Tau, assessed in tau. P301L mice that model tauopathy

C Theunis, N Crespo-Biel, V Gafner, M Pihlgren… - PloS one, 2013 - journals.plos.org
Progressive aggregation of protein Tau into oligomers and fibrils correlates with cognitive
decline and synaptic dysfunction, leading to neurodegeneration in vulnerable brain regions …

Recent advances in hydrogen research as a therapeutic medical gas

CS Huang, T Kawamura, Y Toyoda… - Free radical …, 2010 - Taylor & Francis
Recent basic and clinical research has revealed that hydrogen is an important physiological
regulatory factor with antioxidant, anti-inflammatory and anti-apoptotic protective effects on …

Amyloid cascade in Alzheimer's disease: Recent advances in medicinal chemistry

T Mohamed, A Shakeri, PPN Rao - European journal of medicinal chemistry, 2016 - Elsevier
Alzheimer's disease is of major concern all over the world due to a number of factors
including (i) an aging population (ii) increasing life span and (iii) lack of effective …

[HTML][HTML] Genetic aspects of Alzheimer disease

TD Bird - Genetics in Medicine, 2008 - Elsevier
Alzheimer disease is the most common cause of dementia and represents a major public
health problem. The neuropathologic findings of amyloid-β plaques and tau containing …

Depression and Alzheimer's disease: neurobiological links and common pharmacological targets

F Caraci, A Copani, F Nicoletti, F Drago - European journal of …, 2010 - Elsevier
Depression is one of the most prevalent and life-threatening forms of mental illnesses,
whereas Alzheimer's disease is a neurodegenerative disorder that affects more than 37 …