Targeting angiogenesis has remained one of the important aspects in disease biology in
general and cancer in particular. Currently (June 2023), over 593 clinical trials have been …

Angiogenesis significantly influences the carcinogenesis of thymic epithelial tumors (TET).
Both thymomas and thymic carcinoma (TC) overexpress VEGF-A and VEGFR-1 and-2. This …

Esophageal cancer (EC) treatment via anti‐angiogenic therapy faces challenges due to non‐
cytotoxicity and non‐specific biodistribution of the anti‐angiogenic agents. Hence, the quest …

During tumor development, the tumor itself must continuously generate new blood vessels to
meet their growth needs while also allowing for tumor invasion and metastasis. One of the …

Introduction: Vasculogenic mimicry (VM) represents a novel form of tumor angiogenesis that
is associated with tumor invasiveness and drug resistance. However, the VM landscape …

Bevacizumab, a recombinant humanized monoclonal antibody targeting vascular
endothelial growth factor A (VEGFA), is pivotal in treating various malignancies (Zondor and …

Simple Summary Peritoneum is the most common metastasis site of gastric cancer, and
angiogenesis plays a key role in peritoneal metastasis which the specific mechanism of is …

Lung cancer is a deeply malignant tumor with high incidence and mortality. Despite the
rapid development of diagnosis and treatment technology, abundant patients with lung …

癌症发病率与年龄密切相关， 75% 的非小细胞肺癌（ non-small cell lung cancer, NSCLC）
患者年龄均≥ 65 岁。 免疫检查点抑制剂（ immune checkpoint inhibitors, ICIs） …

The interplay between vascularization and macrophage-induced immune suppression plays
a crucial role in melanoma treatment. In this study, we propose a novel combination …