Early diagnosis of Alzheimer's disease: the role of biomarkers including advanced EEG signal analysis. Report from the IFCN-sponsored panel of experts
PM Rossini, R Di Iorio, F Vecchio, M Anfossi… - Clinical …, 2020 - Elsevier
Alzheimer's disease (AD) is the most common neurodegenerative disease among the
elderly with a progressive decline in cognitive function significantly affecting quality of life …
elderly with a progressive decline in cognitive function significantly affecting quality of life …
EEG and ERP biomarkers of Alzheimer's disease: a critical review.
A Horvath, A Szucs, G Csukly, A Sakovics… - Frontiers in bioscience …, 2018 - real.mtak.hu
Here we critically review studies that used electroencephalography (EEG) or event-related
potential (ERP) indices as a biomarker of Alzheimer's disease. In the first part we overview …
potential (ERP) indices as a biomarker of Alzheimer's disease. In the first part we overview …
The LIFE-Adult-Study: objectives and design of a population-based cohort study with 10,000 deeply phenotyped adults in Germany
M Loeffler, C Engel, P Ahnert, D Alfermann, K Arelin… - BMC public health, 2015 - Springer
Abstract Background The LIFE-Adult-Study is a population-based cohort study, which has
recently completed the baseline examination of 10,000 randomly selected participants from …
recently completed the baseline examination of 10,000 randomly selected participants from …
Effects of a specially designed aerobic dance routine on mild cognitive impairment
Y Zhu, H Wu, M Qi, S Wang, Q Zhang… - … interventions in aging, 2018 - Taylor & Francis
Background Mild cognitive impairment (MCI) is known as a transitional stage or phase
between normal aging and dementia. In addition, it is associated with an increased risk of …
between normal aging and dementia. In addition, it is associated with an increased risk of …
Predictive Power of Cognitive Biomarkers in Neurodegenerative Disease Drug Development: Utility of the P300 Event‐Related Potential
J Olichney, J Xia, KJ Church, HJ Moebius - Neural Plasticity, 2022 - Wiley Online Library
Neurodegenerative diseases, such as Alzheimer's disease (AD), and their associated
deterioration of cognitive function are common causes of disability. The slowly developing …
deterioration of cognitive function are common causes of disability. The slowly developing …
Relationships between the resting-state network and the P3: Evidence from a scalp EEG study
The P3 is an important event-related potential that can be used to identify neural activity
related to the cognitive processes of the human brain. However, the relationships, especially …
related to the cognitive processes of the human brain. However, the relationships, especially …
[HTML][HTML] Inter-subject P300 variability relates to the efficiency of brain networks reconfigured from resting-to task-state: evidence from a simultaneous event-related …
The P300 event-related potential (ERP) varies across individuals, and exploring this
variability deepens our knowledge of the event, and scope for its potential applications …
variability deepens our knowledge of the event, and scope for its potential applications …
Safety, tolerability, pharmacokinetics, and pharmacodynamics of the positive modulator of HGF/MET, fosgonimeton, in healthy volunteers and subjects with …
X Hua, K Church, W Walker, P L'Hostis… - Journal of …, 2022 - content.iospress.com
Background: Fosgonimeton (ATH-1017) is being developed as a first-in-class regenerative
therapy for people with Alzheimer's disease (AD) and dementia; potentially improving …
therapy for people with Alzheimer's disease (AD) and dementia; potentially improving …
Using event-related potential P300 as an electrophysiological marker for differential diagnosis and to predict the progression of mild cognitive impairment: a meta …
S Jiang, C Qu, F Wang, Y Liu, Z Qiao, X Qiu… - Neurological …, 2015 - Springer
P300 event-related potential component may sensitively predict mild cognitive impairment
(MCI) progression. Here, pooled effect size estimates of P300 amplitude and latency were …
(MCI) progression. Here, pooled effect size estimates of P300 amplitude and latency were …
Impaired phasic discharge of locus coeruleus neurons based on persistent high tonic discharge—a new hypothesis with potential implications for neurodegenerative …
K Janitzky - Frontiers in neurology, 2020 - frontiersin.org
The locus coeruleus (LC) is a small brainstem nucleus with widely distributed noradrenergic
projections to the whole brain, and loss of LC neurons is a prominent feature of age-related …
projections to the whole brain, and loss of LC neurons is a prominent feature of age-related …