Onychomycosis: a review

AK Gupta, N Stec, RC Summerbell… - Journal of the …, 2020 - Wiley Online Library
Onychomycosis is a fungal infection of the nail, causing discoloration and thickening of the
affected nail plate, and is the most common nail infection worldwide. Onychomycosis was …

Understanding the formidable nail barrier: A review of the nail microstructure, composition and diseases

S Baswan, GB Kasting, SK Li, R Wickett, B Adams… - Mycoses, 2017 - Wiley Online Library
The topical treatment of nail fungal infections has been a focal point of nail research in the
past few decades as it offers a much safer and focused alternative to conventional oral …

Efinaconazole 10% solution in the treatment of toenail onychomycosis: two phase III multicenter, randomized, double-blind studies

BE Elewski, P Rich, R Pollak, DM Pariser… - Journal of the American …, 2013 - Elsevier
BACKGROUND: Onychomycosis is a common nail infection, often resulting in nail plate
damage and deformity. Topical lacquer treatments have negligible efficacy. Oral treatments …

Topical delivery of antifungal agents

IP Kaur, S Kakkar - Expert opinion on drug delivery, 2010 - Taylor & Francis
Importance of the field: Superficial fungal infections of skin, hair, nails and the eye are
among the most widespread diseases known to man. Topical therapy is the most favored …

Treatment and management strategies of onychomycosis

R Aggarwal, M Targhotra, B Kumar, PK Sahoo… - Journal de mycologie …, 2020 - Elsevier
Onychomycosis is one of the most prevalent and severe nail fungal infections, which is
affecting a wide population across the globe. It leads to variations like nail thickening …

Updated perspectives on the diagnosis and management of onychomycosis

JM Falotico, SR Lipner - Clinical, Cosmetic and Investigational …, 2022 - Taylor & Francis
Onychomycosis is the most common nail disease encountered in clinical practice and can
cause pain, difficulty with ambulation, and psycho-social problems. A thorough history and …

Enhancing the nail permeability of topically applied drugs

S Murdan - Expert opinion on drug delivery, 2008 - Taylor & Francis
The topical therapy of nail diseases, especially of onychomycosis, and to a smaller extent, of
nail psoriasis, is desirable to avoid the side effects associated with their systemic therapy, to …

Terbinafine Hydrochloride Trans-ungual Delivery via Nanovesicular Systems: In Vitro Characterization and Ex Vivo Evaluation

NI Elsherif, RN Shamma, G Abdelbary - Aaps Pharmscitech, 2017 - Springer
Treating a nail infection like onychomycosis is challenging as the human nail plate acts as a
formidable barrier against all drug permeation. Available oral and topical treatments have …

Antifungal Activity of Nanocapsule Suspensions Containing Tea Tree Oil on the Growth of Trichophyton rubrum

FC Flores, JA De Lima, RF Ribeiro, SH Alves… - Mycopathologia, 2013 - Springer
The aim of this study was to evaluate, for the first time, the antifungal efficacy of
nanocapsules and nanoemulsions containing Melaleuca alternifolia essential oil (tea tree …

Science of the nail apparatus

D de Berker, BS Ruben, R Baran - Baran & Dawber's diseases …, 2019 - Wiley Online Library
This chapter provides the scientific backdrop to the interpretation and understanding of
many diseases of the nails and their management. Embryogenesis represents the original …