Reactive oxygen species (ROS) are continuously produced in living cells due to metabolic
and biochemical reactions and due to exposure to physical, chemical and biological agents …

In this review, primary attention is given to the antioxidant (and prooxidant) activity of
polyphenols arising from their interactions with iron both in vitro and in vivo. In addition, an …

Since the appearance in 1985 of the book,'Oxidative Stress'(1), the biomedical area in
particular has increasingly utilized this term in order to denote a challenge of the biological …

This paper assesses critically the science base that underpins the argument that oxidative
damage is a significant causative factor in the development of human diseases and that …

Protein oxidation is defined here as the covalent modification of a protein induced either
directly by reactive oxygen species or indirectly by reaction with secondary by-products of …

In living cells reactive oxygen species (ROS) are formed continuously as a consequence of
metabolic and other biochemical reactions as well as external factors. Some ROS have …

The study of DNA oxidation has progressed from an exploratory phase, during which its
basic biochemistry was established, into a field branching out into numerous areas. Early …

Reactive oxygen species and reactive nitrogen species are formed in the human body.
Endogenous antioxidant defences are inadequate to scavenge them completely, so that …

Human diploid fibroblast cells cease growth in culture after a finite number of population
doublings. To address the cause of growth cessation in senescent IMR-90 human fibroblast …

The mitochondrion is a major source of reactive oxygen species (ROS). Superoxide (O2•−)
is generated under specific bioenergetic conditions at several sites within the electron …