Asthma is a chronic inflammatory airway disease associated with type 2 cytokines
interleukin-4 (IL-4), IL-5, and IL-13, which promote airway eosinophilia, mucus …

Executive summary Asthma is responsible for considerable global morbidity and health-care
costs. Substantial progress was made against key outcomes such as hospital admissions …

Antecedentes Esta la segunda actualización de una revisión publicada anteriormente en la
Biblioteca Cochrane (2015, primera actualización en 2017). La interleucina 5 (IL‐5) es la …

Asthma is a chronic inflammatory disorder of the airways. While the local infiltration of
eosinophils and mast cells, and their role in the disease have long been recognized …

Cytokines play a key role in orchestrating and perpetuating the chronic airway inflammation
in asthma and chronic obstructive pulmonary disease (COPD), making them attractive …

Asthma is a common disease that affects 300 million people worldwide. Given the large
number of eosinophils in the airways of people with mild asthma, and verified by data from …

Asthma varies considerably across the life course. Childhood asthma is known for its overall
high prevalence with a male predominance prior to puberty, common remission, and rare …

Non‐T2 asthma is traditionally defined as asthma without features of T2 asthma. The
definition is arbitrary and is generally based on the presence of neutrophils in sputum, or the …

The term “eosinophilic” asthma (EA) generally refers to the clinical inflammatory phenotype
of asthma wherein a significant number of sputum, airway, and/or blood eosinophils are …

Asthma and obesity are two epidemics affecting the developed world. The relationship
between obesity and both asthma and severe asthma appears to be weight-dependent …