Microfluidics and surface-enhanced Raman spectroscopy, a win–win combination?

R Panneerselvam, H Sadat, EM Höhn, A Das… - Lab on a Chip, 2022 - pubs.rsc.org
With the continuous development in nanoscience and nanotechnology, analytical
techniques like surface-enhanced Raman spectroscopy (SERS) render structural and …

Progress of inertial microfluidics in principle and application

Y Gou, Y Jia, P Wang, C Sun - Sensors, 2018 - mdpi.com
Inertial microfluidics has become a popular topic in microfluidics research for its good
performance in particle manipulation and its advantages of simple structure, high …

Nanoscale tweezers for single-cell biopsies

BP Nadappuram, P Cadinu, A Barik… - Nature …, 2019 - nature.com
Much of the functionality of multicellular systems arises from the spatial organization and
dynamic behaviours within and between cells. Current single-cell genomic methods only …

In Situ Single-Cell Surgery and Intracellular Organelle Manipulation Via Thermoplasmonics Combined Optical Trapping

X Zhao, Y Shi, T Pan, D Lu, J Xiong, B Li, H Xin - Nano Letters, 2021 - ACS Publications
Microsurgery and biopsies on individual cells in a cellular microenvironment are of great
importance to better understand the fundamental cellular processes at subcellular and even …

High‐Preservation Single‐Cell Operation through a Photo‐responsive Hydrogel‐Nanopipette System

ZY Li, YY Liu, YJ Li, W Wang, Y Song… - Angewandte Chemie …, 2021 - Wiley Online Library
Single‐cell and in situ cell‐based operation with nanopipette approach offers a possibility to
elucidate the intracellular processes and may aid the improvement of therapy efficiency and …

Nanoscale Methods for Longitudinal Extraction of Intracellular Contents

YJ Quek, A Tay - Advanced Materials, 2024 - Wiley Online Library
Longitudinal analysis of intracellular contents including gene and protein expression is
crucial for deciphering the fundamentally dynamic nature of cells. This offers invaluable …

Single-entity electrochemistry at confined sensing interfaces

YL Ying, J Wang, AR Leach, Y Jiang, R Gao… - Science China …, 2020 - Springer
Measurements at the single-entity level provide more precise diagnosis and understanding
of basic biological and chemical processes. Recent advances in the chemical measurement …

Semi-implantable bioelectronics

J Fang, S Huang, F Liu, G He, X Li, X Huang, H Chen… - Nano-Micro Letters, 2022 - Springer
Developing techniques to effectively and real-time monitor and regulate the interior
environment of biological objects is significantly important for many biomedical engineering …

Rapid and label-free identification of single leukemia cells from blood in a high-density microfluidic trapping array by fluorescence lifetime imaging microscopy

DH Lee, X Li, N Ma, MA Digman, AP Lee - Lab on a Chip, 2018 - pubs.rsc.org
The rapid screening and isolation of single leukemia cells from blood has become critical for
early leukemia detection and tumor heterogeneity interrogation. However, due to the size …

Recent advances in single-cell subcellular sampling

A Sahota, AM Cabrejos, Z Kwan… - Chemical …, 2023 - pubs.rsc.org
Recent innovations in single-cell technologies have opened up exciting possibilities for
profiling the omics of individual cells. Minimally invasive analysis tools that probe and …