The nucleus pulposus microenvironment in the intervertebral disc: the fountain of youth?
The intervertebral disc (IVD) is a complex tissue, and its degeneration remains a problem for
patients, without significant improvement in treatment strategies. This mostly age-related …
patients, without significant improvement in treatment strategies. This mostly age-related …
Spine biomechanical testing methodologies: the controversy of consensus vs scientific evidence
Biomechanical testing methodologies for the spine have developed over the past 50 years.
During that time, there have been several paradigm shifts with respect to techniques. These …
During that time, there have been several paradigm shifts with respect to techniques. These …
[HTML][HTML] Exploration of the influence of different biomimetic designs of 3D printed multi-material artificial spinal disc on the natural mechanics restoration
One of the great challenges of artificial spinal disc (ASD) design lies in the reproduction of
the complex mechanics of an intervertebral disc (IVD) that is characterized by a viscoelastic …
the complex mechanics of an intervertebral disc (IVD) that is characterized by a viscoelastic …
Sensitivity of intervertebral disc finite element models to internal geometric and non-geometric parameters
Finite element models are useful for investigating internal intervertebral disc (IVD)
behaviours without using disruptive experimental techniques. Simplified geometries are …
behaviours without using disruptive experimental techniques. Simplified geometries are …
Quantifying deformations and strains in human intervertebral discs using Digital Volume Correlation combined with MRI (DVC-MRI)
Physical disruptions to intervertebral discs (IVDs) can cause mechanical changes that lead
to degeneration and to low back pain which affects 75% of us in our lifetimes. Quantifying …
to degeneration and to low back pain which affects 75% of us in our lifetimes. Quantifying …
The effect of degeneration on internal strains and the mechanism of failure in human intervertebral discs analyzed using digital volume correlation (DVC) and ultra …
The intervertebral disc (IVD) plays a main role in absorbing and transmitting loads within the
spinal column. Degeneration alters the structural integrity of the IVDs and causes pain …
spinal column. Degeneration alters the structural integrity of the IVDs and causes pain …
[HTML][HTML] The influence of geometry on intervertebral disc stiffness
Geometry plays an important role in intervertebral disc (IVD) mechanics. Previous
computational studies have found a link between IVD geometry and stiffness. However, few …
computational studies have found a link between IVD geometry and stiffness. However, few …
An in vitro comparison of three nucleus pulposus removal techniques for partial intervertebral disc replacement: An ultra‐high resolution MRI study
Background Nuclectomy, also known as nucleotomy, is a percutaneous surgical procedure
performed to remove nucleus material from the center of the disc. Multiple techniques have …
performed to remove nucleus material from the center of the disc. Multiple techniques have …
Subject-specific geometry of FE lumbar spine models for the replication of fracture locations using dynamic drop tests
LK Rieger, A Shah, S Schick, DB Draper… - Annals of Biomedical …, 2024 - Springer
For traumatic lumbar spine injuries, the mechanisms and influence of anthropometrical
variation are not yet fully understood under dynamic loading. Our objective was to evaluate …
variation are not yet fully understood under dynamic loading. Our objective was to evaluate …
Influence of testing environment and loading rate on intervertebral disc compressive mechanics: an assessment of repeatability at three different laboratories
In vitro mechanical testing of intervertebral discs is crucial for basic science and pre‐clinical
testing. Generally, these tests aim to replicate in vivo conditions, but simplifications are …
testing. Generally, these tests aim to replicate in vivo conditions, but simplifications are …