Pre-eclampsia

E Dimitriadis, DL Rolnik, W Zhou… - Nature reviews Disease …, 2023 - nature.com
Pre-eclampsia is a life-threatening disease of pregnancy unique to humans and a leading
cause of maternal and neonatal morbidity and mortality. Women who survive pre-eclampsia …

Regulatory mechanism and research progress of ferroptosis in obstetrical and gynecological diseases

X Wang, Y Wei, F Wei, H Kuang - Frontiers in Cell and …, 2023 - frontiersin.org
Ferroptosis is a novel type of regulated cell death driven by iron-dependent lipid
peroxidation, which is distinguished from traditional types of programmed cell death, such as …

Placental cell type deconvolution reveals that cell proportions drive preeclampsia gene expression differences

KA Campbell, JA Colacino, M Puttabyatappa… - Communications …, 2023 - nature.com
The placenta mediates adverse pregnancy outcomes, including preeclampsia, which is
characterized by gestational hypertension and proteinuria. Placental cell type heterogeneity …

Integration of Antioxidant Activity Assays Data of Stevia Leaf Extracts: A Systematic Review and Meta-Analysis

M Papaefthimiou, PI Kontou, PG Bagos, GG Braliou - Antioxidants, 2024 - mdpi.com
Stevia rebaudiana Bertoni, a no-calorie natural sweetener, contains a plethora of
polyphenols that exert antioxidant properties with potential medicinal significance. Due to …

Comprehensive transcriptome mining identified the gene expression signature and differentially regulated pathways of the late-onset preeclampsia

H Saei, A Govahi, A Abiri, M Eghbali, M Abiri - Pregnancy Hypertension, 2021 - Elsevier
Preeclampsia (PE) is categorized as a pregnancy-related hypertensive disorder and is a
serious concern in pregnancies. Several factors, including genetic factors (placenta gene …

Genome-Wide Copy Number Variant and High-Throughput Transcriptomics Analyses of Placental Tissues Underscore Persisting Child Susceptibility in At-Risk …

D Czamara, C Cruceanu, M Lahti-Pulkkinen… - International Journal of …, 2022 - mdpi.com
Several studies have shown that children from pregnancies with estimated first-trimester risk
based on fetal nuchal translucency thickness and abnormal maternal serum pregnancy …

[HTML][HTML] Comparison of maternal serum NRG-4 levels in healthy and preeclamptic pregnancies

K Yakut, FH Öztürk, DF Öcal, B Yakıştıran… - Journal of the Turkish …, 2022 - ncbi.nlm.nih.gov
Objective: The new adipokine, neuregulin-4 (NRG-4), acts as a signaling protein and plays a
role in lipogenesis, inflammatory events and atherosclerosis. The aim was to investigate …

The Polymorphic Locus rs167479 of the RGL3 Gene Is Associated with the Risk of Severe Preeclampsia

MY Abramova, IV Ponomarenko… - Russian Journal of …, 2022 - Springer
In this work, the associations of polymorphism of candidate genes of arterial hypertension
with the development of severe preeclampsia (PE) in the population of the Central …

[HTML][HTML] Integrated analysis of transcriptomic datasets to identify placental biomarkers of spontaneous preterm birth

NC Sobhani, R Mernoff, M Abraha, CN Okorie… - Placenta, 2022 - Elsevier
Introduction Preterm birth (PTB) remains the leading cause of neonatal morbidity and
mortality in the United States. The mechanisms underlying spontaneous PTB (SPTB) involve …

[HTML][HTML] Blood biomarkers representing maternal-fetal interface tissues used to predict early-and late-onset preeclampsia but not COVID-19 infection

H Sufriyana, HM Salim, AR Muhammad, YW Wu… - Computational and …, 2022 - Elsevier
Background A well-known blood biomarker (soluble fms-like tyrosinase-1 [sFLT-1]) for
preeclampsia, ie, a pregnancy disorder, was found to predict severe COVID-19, including in …