Understanding the role of sensorimotor beta oscillations

J Barone, HE Rossiter - Frontiers in Systems Neuroscience, 2021 - frontiersin.org
Beta oscillations have been predominantly observed in sensorimotor cortices and basal
ganglia structures and they are thought to be involved in somatosensory processing and …

Neurophysiological mechanisms of deep brain stimulation across spatiotemporal resolutions

WJ Neumann, LA Steiner, L Milosevic - Brain, 2023 - academic.oup.com
Deep brain stimulation is a neuromodulatory treatment for managing the symptoms of
Parkinson's disease and other neurological and psychiatric disorders. Electrodes are …

Adaptive deep brain stimulation in advanced Parkinson disease

S Little, A Pogosyan, S Neal, B Zavala… - Annals of …, 2013 - Wiley Online Library
Objective Brain–computer interfaces (BCIs) could potentially be used to interact with
pathological brain signals to intervene and ameliorate their effects in disease states. Here …

Bilateral adaptive deep brain stimulation is effective in Parkinson's disease

S Little, M Beudel, L Zrinzo, T Foltynie… - Journal of Neurology …, 2016 - jnnp.bmj.com
Introduction & objectives Adaptive deep brain stimulation (aDBS) uses feedback from brain
signals to guide stimulation. A recent acute trial of unilateral aDBS showed that aDBS can …

The indirect pathway of the basal ganglia promotes transient punishment but not motor suppression

BR Isett, KP Nguyen, JC Schwenk, JR Yurek… - Neuron, 2023 - cell.com
Optogenetic stimulation of Adora2a receptor-expressing spiny projection neurons (A2A-
SPNs) in the striatum drives locomotor suppression and transient punishment, results …

Deep brain stimulation modulates synchrony within spatially and spectrally distinct resting state networks in Parkinson's disease

A Oswal, M Beudel, L Zrinzo, P Limousin, M Hariz… - Brain, 2016 - academic.oup.com
Chronic dopamine depletion in Parkinson's disease leads to progressive motor and
cognitive impairment, which is associated with the emergence of characteristic patterns of …

[HTML][HTML] Toward electrophysiology-based intelligent adaptive deep brain stimulation for movement disorders

WJ Neumann, RS Turner, B Blankertz, T Mitchell… - …, 2019 - Elsevier
Deep brain stimulation (DBS) represents one of the major clinical breakthroughs in the age
of translational neuroscience. In 1987, Benabid and colleagues demonstrated that high …

Machine learning for adaptive deep brain stimulation in Parkinson's disease: closing the loop

AM Oliveira, L Coelho, E Carvalho… - Journal of …, 2023 - Springer
Parkinson's disease (PD) is the second most common neurodegenerative disease bearing a
severe social and economic impact. So far, there is no known disease modifying therapy …

Temporal evolution of beta bursts in the parkinsonian cortical and basal ganglia network

H Cagnan, N Mallet, CKE Moll… - Proceedings of the …, 2019 - National Acad Sciences
Beta frequency oscillations (15 to 35 Hz) in cortical and basal ganglia circuits become
abnormally synchronized in Parkinson's disease (PD). How excessive beta oscillations …

[HTML][HTML] Deep brain stimulation for movement disorders of basal ganglia origin: restoring function or functionality?

T Wichmann, MR DeLong - Neurotherapeutics, 2016 - Elsevier
Deep brain stimulation (DBS) is highly effective for both hypo-and hyperkinetic movement
disorders of basal ganglia origin. The clinical use of DBS is, in part, empiric, based on the …