Applications of isothermal titration calorimetry in pure and applied research—survey of the literature from 2010

R Ghai, RJ Falconer, BM Collins - Journal of Molecular …, 2012 - Wiley Online Library
Isothermal titration calorimetry (ITC) is a biophysical technique for measuring the formation
and dissociation of molecular complexes and has become an invaluable tool in many …

Application of isothermal titration calorimetry as a tool to study natural product interactions

O Callies, AH Daranas - Natural product reports, 2016 - pubs.rsc.org
Covering: up to February 2015 Over the past twenty-five years, isothermal titration
calorimetry (ITC) has become a potent tool for the study a great variety of molecular …

A comprehensive insight into binding of hippuric acid to human serum albumin: a study to uncover its impaired elimination through hemodialysis

N Zaidi, MR Ajmal, G Rabbani, E Ahmad, RH Khan - PloS one, 2013 - journals.plos.org
Binding of hippuric acid (HA), a uremic toxin, with human serum albumin (HSA) has been
examined by isothermal titration calorimetry (ITC), differential scanning calorimetry (DSC) …

Interaction of 5-fluoro-5′-deoxyuridine with human serum albumin under physiological and non-physiological condition: A biophysical investigation

M Ishtikhar, G Rabbani, RH Khan - Colloids and Surfaces B: Biointerfaces, 2014 - Elsevier
Uridine analogs 5′ dFUrd (a cytotoxic metabolite of a prodrug capecitabine that
enzymatically converted into 5′ dFUrd) commonly used in the treatment of advanced …

Binding and displacement study of gentamicin, 5-fluorouracil, oxytetracycline and rolitetracycline with (BSA: Drug2) complex using spectroscopic and calorimetric …

M Thorve, N Kishore - International Journal of Biological Macromolecules, 2024 - Elsevier
Understanding of energetics of interactions between drug and protein is essential in
pharmacokinetics and pharmacodynamics study. The binding affinity (K) helps in …

Discovery of harmaline as a potent inhibitor of sphingosine kinase-1: a chemopreventive role in lung cancer

S Roy, T Mohammad, P Gupta, R Dahiya, S Parveen… - ACS …, 2020 - ACS Publications
The sphingosine kinase-1/sphingosine-1-phosphate pathway is linked with the cancer
progression and survival of the chemotherapy-challenged cells. Sphingosine kinase-1 …

Ecological risk assessment of amoxicillin, enrofloxacin, and neomycin: are their current levels in the freshwater environment safe?

S Lee, C Kim, X Liu, S Lee, Y Kho, WK Kim, P Kim… - Toxics, 2021 - mdpi.com
Veterinary pharmaceuticals may cause unexpected adverse effects on non-target aquatic
species. While these pharmaceuticals were previously identified as priority compounds in …

Interaction of human serum albumin with short polyelectrolytes: a study by calorimetry and computer simulations

S Yu, X Xu, C Yigit, M van der Giet, W Zidek… - Soft Matter, 2015 - pubs.rsc.org
We present a comprehensive study of the interaction of human serum albumin (HSA) with
poly (acrylic acid)(PAA; number average degree of polymerization: 25) in aqueous solution …

Potential inhibitors designed against NDM-1 type metallo-β-lactamases: an attempt to enhance efficacies of antibiotics against multi-drug-resistant bacteria

AU Khan, A Ali, Danishuddin, G Srivastava… - Scientific reports, 2017 - nature.com
NDM-1 and its variants are the most prevalent types of metallo-β-lactamases, hydrolyze
almost all antibiotics of β-lactam group leading to multiple-drug resistance in bacteria. No …

Co-encapsulation of (−)-epigallocatechin-3-gallate and piceatannol/oxyresveratrol in β-lactoglobulin: effect of ligand–protein binding on the antioxidant activity …

T Liu, M Liu, H Liu, Y Ren, Y Zhao, H Yan, Q Wang… - Food & Function, 2021 - pubs.rsc.org
The co-encapsulation of multiple bioactive components in a carrier may produce synergistic
effects and improve health benefits. In this study, the interactions of β-lactoglobulin (β-LG) …