The laboratory rat as an animal model for osteoporosis research

PP Lelovas, TT Xanthos, SE Thoma… - Comparative …, 2008 - ingentaconnect.com
Osteoporosis is an important systemic disorder, affecting mainly Caucasian women, with a
diverse and multifactorial etiology. A large variety of animal species, including rodents …

A four-season molecule: osteocalcin. Updates in its physiological roles

G Lombardi, S Perego, L Luzi, G Banfi - Endocrine, 2015 - Springer
Osteocalcin (OC) is the main non-collagenous hydroxyapatite-binding protein synthesized
by osteoblasts, odontoblasts, and hypertrophic chondrocytes. It has a regulatory role in …

The presence of both an energy deficiency and estrogen deficiency exacerbate alterations of bone metabolism in exercising women

MJ De Souza, SL West, SA Jamal, GA Hawker… - Bone, 2008 - Elsevier
BACKGROUND: Bone loss in amenorrheic athletes has been attributed to energy deficiency-
related suppression of bone formation, but not increased resorption despite …

Autogenous bone chips: influence of a new piezoelectric device (Piezosurgery®) on chip morphology, cell viability and differentiation

G Chiriac, M Herten, F Schwarz… - Journal of clinical …, 2005 - Wiley Online Library
Aim: The aim of the present study was to investigate the influence of a new piezoelectric
device, designed for harvesting autogenous bone chips from intra‐oral sites, on chip …

Decellularization and delipidation protocols of bovine bone and pericardium for bone grafting and guided bone regeneration procedures

C Gardin, S Ricci, L Ferroni, R Guazzo, L Sbricoli… - PloS one, 2015 - journals.plos.org
The combination of bone grafting materials with guided bone regeneration (GBR)
membranes seems to provide promising results to restore bone defects in dental clinical …

Antiepileptics and bone health

C Meier, ME Kraenzlin - Therapeutic advances in …, 2011 - journals.sagepub.com
In recent years there has been increasing evidence suggesting that epilepsy and its
treatment can have adverse effects on bone mineralization and calcium metabolism. Many …

Biochemical markers of bone turnover, hip bone loss, and fracture in older men: the MrOS study

DC Bauer, P Garnero, SL Harrison… - Journal of Bone and …, 2009 - academic.oup.com
We used data from the Osteoporotic Fractures in Men (MrOS) study to test the hypothesis
that men with higher levels of bone turnover would have accelerated bone loss and an …

Runx2/Cbfa1 stimulates transdifferentiation of primary skeletal myoblasts into a mineralizing osteoblastic phenotype

CA Gersbach, BA Byers, GK Pavlath… - Experimental cell research, 2004 - Elsevier
Runx2, a transcriptional activator downstream of bone morphogenetic protein (BMP)
signaling, is essential to osteoblastic differentiation and bone formation and maintenance …

Glucocorticoid-induced osteogenesis is negatively regulated by Runx2/Cbfa1 serine phosphorylation

JE Phillips, CA Gersbach, AM Wojtowicz… - Journal of cell …, 2006 - journals.biologists.com
Glucocorticoid hormones have complex stimulatory and inhibitory effects on skeletal
metabolism. Endogenous glucocorticoid signaling is required for normal bone formation in …

Biochemical markers of bone turnover in osteoporosis

P Szulc, DC Bauer, R Eastell - Marcus and Feldman's Osteoporosis, 2021 - Elsevier
Bone turnover markers (BTMs) are divided into the markers of bone formation and those of
bone resorption. N-terminal collagen type I extension propeptide and serum C-terminal …