Serum albumin in health and disease: esterase, antioxidant, transporting and signaling properties

DA Belinskaia, PA Voronina, VI Shmurak… - International journal of …, 2021 - mdpi.com
Being one of the main proteins in the human body and many animal species, albumin plays
a decisive role in the transport of various ions—electrically neutral and charged molecules …

Receptor for advanced glycation end products (RAGE): a pivotal hub in immune diseases

Q Yue, Y Song, Z Liu, L Zhang, L Yang, J Li - Molecules, 2022 - mdpi.com
As a critical molecule in the onset and sustainment of inflammatory response, the receptor
for advanced glycation end products (RAGE) has a variety of ligands, such as advanced …

Long COVID (PASC) is maintained by a self-sustaining pro-inflammatory TLR4/RAGE-loop of S100A8/A9> TLR4/RAGE signalling, inducing chronic expression of IL …

RD Holms - Immuno, 2022 - mdpi.com
Long COVID, also referred to as Post-Acute Sequelae of COVID (PASC), is probably
triggered during SARS-CoV-2 infection and acute COVID-19 by SARS-CoV-2 Spike-protein …

Smoking and vaping alter genes related to mechanisms of SARS-CoV-2 susceptibility and severity: a systematic review and meta-analysis

R Bowsher, TH Marczylo, K Gooch… - European …, 2024 - publications.ersnet.org
Background Evidence for the impact of smoking on coronavirus disease 2019 (COVID-19) is
contradictory, and there is little research on vaping. Here we provide greater clarity on …

Integrative role of albumin: evolutionary, biochemical and pathophysiological aspects

DA Belinskaia, PA Voronina, NV Goncharov - Journal of evolutionary …, 2021 - Springer
Being one of the main proteins in the human body and many animal species, albumin plays
a crucial role in the transport of various ions, electrically neutral molecules and in …

Oxidative stress and inflammatory markers in patients with COVID-19: Potential role of RAGE, HMGB1, GFAP and COX-2 in disease severity

FRS Passos, L Heimfarth, BS Monteiro… - International …, 2022 - Elsevier
Background SARS-CoV-2 infection can lead to the abnormal induction of cytokines and a
dysregulated hyperinflammatory state that is implicated in disease severity and risk of death …

Molecular and immune signatures, and pathological trajectories of fatal COVID‐19 lungs defined by in situ spatial single‐cell transcriptome analysis

A Das, W Meng, Z Liu, MM Hasib… - Journal of Medical …, 2023 - Wiley Online Library
Despite intensive studies during the last 3 years, the pathology and underlying molecular
mechanism of coronavirus disease 2019 (COVID‐19) remain poorly defined. In this study …

HMGB1 mediates microbiome-immune axis dysregulation underlying reduced neutralization capacity in obesity-related post-acute sequelae of SARS-CoV-2

NC Rubas, R Peres, BP Kunihiro, NP Allan… - Scientific Reports, 2024 - nature.com
While obesity is a risk factor for post-acute sequelae of SARS-CoV-2 infection (PASC," long-
COVID"), the mechanism (s) underlying this phenomenon remains poorly understood. To …

Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Spike Protein S1 Induces Methylglyoxal-Derived Hydroimidazolone/Receptor for Advanced …

D Manfredelli, M Pariano, C Costantini… - International Journal of …, 2023 - mdpi.com
The pathogenesis of coronavirus disease 2019 (COVID-19) is associated with a
hyperinflammatory response. The mechanisms of SARS-CoV-2-induced inflammation are …

Anti-phospholipid antibodies and COVID-19 thrombosis: a co-star, not a supporting actor

FJ Gil-Etayo, S Garcinuño, A Lalueza, R Díaz-Simón… - Biomedicines, 2021 - mdpi.com
Background: COVID-19 clinical features include a hypercoagulable state that resembles the
antiphospholipid syndrome (APS), a disease characterized by thrombosis and presence of …