In amyotrophic lateral sclerosis (ALS), abnormalities in motoneuronal excitability are seen in
early pathogenesis and throughout disease progression. Fully understanding motoneuron …

Mathematical models and computer simulations have the great potential to substantially
increase our understanding of the biophysical behavior of the neuromuscular system. This …

Muscle force is modulated by sequential recruitment and firing rates of motor units (MUs).
However, discrepancies exist in the literature regarding the relationship between MU firing …

Experimental, methodological, and biological variables must be accounted for statistically to
maximize accuracy and comparability of published neuroscience data. However, accounting …

Up to 50% of amputees abandon their prostheses, partly due to rapid degradation of the
control systems, which require frequent recalibration. The goal of this study was to develop a …

The overarching goal was to resolve a major barrier to real-life prosthesis usability—the
rapid degradation of prosthesis control systems, which require frequent recalibrations …

Introduction The understanding of the neurophysiological mechanisms underlying
movement control can be much furthered using computational models of the …

Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disease that affects the
nervous system causing muscle weakness, paralysis, leading to death. Given that …

Spinal cord stimulation (SCS) is a pain management therapy for patients suffering from
specific types of chronic pain conditions that are refractory to conventional medical …

The muscle aging, as a disease entity, is known as Sarcopenia. It is defined as a reduction
of muscle strength/force accompanied by a loss of muscle mass and a decline in physical …