[HTML][HTML] Recommendations for cell-free DNA assay validations: a joint consensus recommendation of the Association for Molecular Pathology and College of …

CM Lockwood, L Borsu, M Cankovic, JSL Earle… - The Journal of molecular …, 2023 - Elsevier
Diagnosing, selecting therapy for, and monitoring cancer in patients using a minimally
invasive blood test represents a significant advance in precision medicine. Wide variability …

Cancer epigenetic biomarkers in liquid biopsy for high incidence malignancies

C Palanca-Ballester, A Rodriguez-Casanova, S Torres… - Cancers, 2021 - mdpi.com
Simple Summary Apart from genetic changes, cancer is characterized by epigenetic
alterations, which indicate modifications in the DNA (such as DNA methylation) and histones …

Epigenetic modifications in prostate cancer

M Sugiura, H Sato, M Kanesaka… - … Journal of Urology, 2021 - Wiley Online Library
Prostate cancer is a major cause of cancer‐related deaths among men worldwide. In
addition to genomic alterations, epigenetic alterations accumulated in prostate cancer have …

Early detection of the major male cancer types in blood-based liquid biopsies using a DNA methylation panel

V Constâncio, SP Nunes, C Moreira-Barbosa… - Clinical …, 2019 - Springer
Abstract Background Lung (LC), prostate (PCa) and colorectal (CRC) cancers are the most
incident in males worldwide. Despite recent advances, optimal population-based cancer …

DNA-methylation-based detection of urological cancer in urine: overview of biomarkers and considerations on biomarker design, source of DNA, and detection …

LK Larsen, GE Lind, P Guldberg, C Dahl - International journal of …, 2019 - mdpi.com
Changes in DNA methylation have been causally linked with cancer and provide promising
biomarkers for detection in biological fluids such as blood, urine, and saliva. The field has …

Deciphering the genetic code of DNA methylation

M Wang, V Ngo, W Wang - Briefings in bioinformatics, 2021 - academic.oup.com
DNA methylation plays crucial roles in many biological processes and abnormal DNA
methylation patterns are often observed in diseases. Recent studies have shed light on cis …

Clinical proteomics for prostate cancer: understanding prostate cancer pathology and protein biomarkers for improved disease management

C Tonry, S Finn, J Armstrong, SR Pennington - Clinical Proteomics, 2020 - Springer
Following the introduction of routine Prostate Specific Antigen (PSA) screening in the early
1990′ s, Prostate Cancer (PCa) is often detected at an early stage. There are also a …

Expression of small noncoding RNAs in urinary exosomes classifies prostate cancer into indolent and aggressive disease

WLW Wang, I Sorokin, I Aleksic, H Fisher… - The Journal of …, 2020 - auajournals.org
Purpose: This is the first report of the development and performance of a platform that
interrogates small noncoding RNAs (sncRNA) isolated from urinary exosomes. The …

Detection of differentially methylated CpGs between tumour and adjacent benign cells in diagnostic prostate cancer samples

LM FitzGerald, C Jung, EM Wong, JHE Joo… - Scientific reports, 2024 - nature.com
Differentially methylated CpG sites (dmCpGs) that distinguish prostate tumour from adjacent
benign tissue could aid in the diagnosis and prognosis of prostate cancer. Previously, the …

[HTML][HTML] Clinical biofluid assays for prostate cancer

T Borbiev, I Kohaar, G Petrovics - Cancers, 2023 - mdpi.com
Simple Summary Prostate cancer (PCa) is the most frequent malignancy, and the second
leading cause of cancer-related death, in men in the United States. PCa detection has been …