Plasmodium vivax vaccine: What is the best way to go?

GTS Veiga, MR Moriggi, JF Vettorazzi… - Frontiers in …, 2023 - frontiersin.org
Malaria is one of the most devastating human infectious diseases caused by Plasmodium
spp. parasites. A search for an effective and safe vaccine is the main challenge for its …

Analysis of Apical Membrane Antigen (AMA)-1 characteristics using bioinformatics tools in order to vaccine design against Plasmodium vivax

F Jahangiri, N Jalallou, M Ebrahimi - Infection, genetics and evolution, 2019 - Elsevier
Plasmodium vivax, an intracellular protozoan, causes malaria which is characterized by
fever, anemia, respiratory distress, liver and spleen enlargement. In spite of attempts to …

[HTML][HTML] Peptide-pulsed dendritic cells' immunomodulating effect regarding Mycobacterium tuberculosis growth in macrophages

CD Sánchez-Barinas, V Vergara-Vanegas… - Immunobiology, 2023 - Elsevier
Mycobacterium tuberculosis is one of the most successful pathogens affecting humans,
being the main cause of tuberculosis. It accounts for most infectious agent-related deaths …

Evaluation of HLA class I and HLA class II allele profile and its relationship with clinical features in patients with alopecia areata: a case–control study

Y Hayran, M Gunindi Korkut, A Öktem… - Journal of …, 2022 - Taylor & Francis
Background Alopecia areata (AA) is an autoimmune disease where autoimmune
dysregulations along with genetic susceptibility are hypothesized to play a role in …

RON2, a novel gene in Babesia bigemina, contains conserved, immunodominant B-cell epitopes that induce antibodies that block merozoite invasion

J Mosqueda, M Hidalgo-Ruiz, DA Calvo-Olvera… - Parasitology, 2019 - cambridge.org
Bovine babesiosis is the most important protozoan disease transmitted by ticks. In
Plasmodium falciparum, another Apicomplexa protozoan, the interaction of rhoptry neck …

Compilation of parasitic immunogenic proteins from 30 years of published research using machine learning and natural language processing

SJ Goodswen, PJ Kennedy, JT Ellis - Scientific Reports, 2022 - nature.com
Abstract The World Health Organisation reported in 2020 that six of the top 10 sources of
death in low-income countries are parasites. Parasites are microorganisms in a relationship …

Genetic sequence characterization and naturally acquired immune response to Plasmodium vivax Rhoptry Neck Protein 2 (PvRON2)

NC Bittencourt, JA Leite, ABIE Silva, TS Pimenta… - Malaria Journal, 2018 - Springer
Background The genetic diversity of malaria antigens often results in allele variant-specific
immunity, imposing a great challenge to vaccine development. Rhoptry Neck Protein 2 …

[PDF][PDF] Bioinformatics characterization of Plasmodium knowlesi apical membrane antigen 1 (PkAMA1) for multi-epitope vaccine design.

A Azazi, FN Haron, KH Chua, YAL Lim, PC Lee… - 2021 - academia.edu
Malaria caused by Plasmodium knowlesi species has become a public health concern,
especially in Malaysia. Plasmodium knowlesi parasite which originates from the macaque …

The persistence of naturally acquired antibodies and memory B cells specific to rhoptry proteins of Plasmodium vivax in patients from areas of low malaria …

P Kochayoo, S Changrob, K Wangriatisak, SK Lee… - Malaria journal, 2019 - Springer
Background Rhoptries are the large, paired, secretory organelles located at the apical tip of
the malaria merozoite that are considered important for parasite invasion processes …

T Cell Peptides Derived from Invasive Stages of Schistosoma mansoni as Potential Schistosomiasis Vaccine

J Lopez-Aban, B Vicente, E Kabbas-Pinango… - Journal of Clinical …, 2021 - mdpi.com
Schistosomiasis is a parasitic disease that affects 143 million people in endemic countries.
This work analyzed overexpressed sequences from the cercaria phase to the early …