Glial KCNQ K+ channels control neuronal output by regulating GABA release from glia in C. elegans

B Graziano, L Wang, OR White, DH Kaplan… - Neuron, 2024 - cell.com
KCNQs are voltage-gated K+ channels that control neuronal excitability and are mutated in
epilepsy and autism spectrum disorder (ASD). KCNQs have been extensively studied in …

Olfactory specificity regulates lipid metabolism through neuroendocrine signaling in Caenorhabditis elegans

AS Mutlu, SM Gao, H Zhang, MC Wang - Nature communications, 2020 - nature.com
Olfactory and metabolic dysfunctions are intertwined phenomena associated with obesity
and neurodegenerative diseases; yet how mechanistically olfaction regulates metabolic …

Phasic/tonic glial GABA differentially transduce for olfactory adaptation and neuronal aging

H Cheng, D Chen, X Li, U Al-Sheikh, D Duan, Y Fan… - Neuron, 2024 - cell.com
Phasic (fast) and tonic (sustained) inhibition of γ-aminobutyric acid (GABA) are fundamental
for regulating day-to-day activities, neuronal excitability, and plasticity. However, the …

Sensory glia detect repulsive odorants and drive olfactory adaptation

D Duan, H Zhang, X Yue, Y Fan, Y Xue, J Shao, G Ding… - Neuron, 2020 - cell.com
Glia are typically considered as supporting cells for neural development and synaptic
transmission. Here, we report an active role of a glia in olfactory transduction. As a …

A glial ClC Cl− channel mediates nose touch responses in C. elegans

J Fernandez-Abascal, CK Johnson, B Graziano… - Neuron, 2022 - cell.com
In touch receptors, glia and accessory cells play a key role in mechanosensation. However,
the mechanisms underlying such regulation are poorly understood. We show, for the first …

Chemosensory detection of polyamine metabolites guides C. elegans to nutritive microbes

B Brissette, L Ficaro, C Li, DR Jones… - Science …, 2024 - science.org
Much is known about molecular mechanisms by which animals detect pathogenic microbes,
but how animals sense beneficial microbes remains poorly understood. The roundworm …

Prominent inhibitory projections guide sensorimotor computation: An invertebrate perspective

S Hughes, T Celikel - Bioessays, 2019 - Wiley Online Library
From single‐cell organisms to complex neural networks, all evolved to provide control
solutions to generate context‐and goal‐specific actions. Neural circuits performing …

Glutamate signaling from a single sensory neuron mediates experience-dependent bidirectional behavior in Caenorhabditis elegans

H Sato, H Kunitomo, X Fei, K Hashimoto, Y Iino - Cell reports, 2021 - cell.com
Orientation and navigation behaviors of animals are modulated by past experiences.
However, little is known about the mechanisms by which sensory inputs are translated into …

Head-tail-head neural wiring underlies gut fat storage in Caenorhabditis elegans temperature acclimation

H Motomura, M Ioroi, K Murakami… - Proceedings of the …, 2022 - National Acad Sciences
Animals maintain the ability to survive and reproduce by acclimating to environmental
temperatures. We showed here that Caenorhabditis elegans exhibited temperature …

[HTML][HTML] Impacts of normative information on college students' energy-saving intentions and behaviors in the dormitory

N Liu, X Luo, X Liu, M Xing - Energy and Built Environment, 2025 - Elsevier
College students' energy-saving behaviors in dormitory buildings are crucial for reducing
energy consumption on university campuses. An information framework aimed at …