Conspectus Conversion of common reactants to diverse products is a key objective of
organic syntheses. Recent developments in transition-metal-catalyzed C–H functionalization …

Abstract Hydrogen-atom-transfer (HAT) is an efficient way for direct Csingle bondH
functionalization of inert Csingle bondH bonds, therefore it has attracted great interests in …

A method for the conversion of pyrimidines into pyrazoles by a formal carbon deletion has
been achieved guided by computational analysis. The pyrimidine heterocycle is the most …

Reported herein is the pyrazole‐directed iridium‐catalyzed enantioselective borylation of
unbiased methylene C− H bonds at the position β to a nitrogen center. The combination of a …

Herein, we report an efficient methodology for the synthesis of alkyl, benzyl, and phenyl
selenoethers of aminopyrazoles and aminouracils by C (sp2)–H functionalization in the …

C− H functionalization is one of the most convenient and powerful tools in the arsenal of
modern chemistry, deservedly nominated as the “Holy Grail” of organic synthesis. A frequent …

A carbene-catalyzed enantio-and diastereoselective [2+ 4] cycloaddition reaction is
developed for quick and efficient access to structurally complex multicyclic pyrano [2, 3-c] …

The catalytic asymmetric electrophilic functionalization of the less reactive N-heteroaromatic
compounds has been reported using the approach of the introduction of an exocyclic amino …

The synthesis of 4-halo-functionalized pyrazoles by electrochemical cascade reactions
between N, N-dimethyl enaminones and proper hydrazine reagents in the presence of a …

Pyrazoles are ubiquitous structures in medicinal chemistry. We report the first regioselective
route to C3-hydroxyarylated pyrazoles obtained through reaction of pyrazole N-oxides with …