Laboratory diagnostics of botulism
M Lindstrom, H Korkeala - Clinical microbiology reviews, 2006 - Am Soc Microbiol
Botulism is a potentially lethal paralytic disease caused by botulinum neurotoxin. Human
pathogenic neurotoxins of types A, B, E, and F are produced by a diverse group of anaerobic …
pathogenic neurotoxins of types A, B, E, and F are produced by a diverse group of anaerobic …
Liquid chromatography–mass spectrometry in food safety
AK Malik, C Blasco, Y Picó - Journal of Chromatography A, 2010 - Elsevier
The use of powerful mass spectrometric detectors in combination with liquid
chromatography has played a vital role to solve many problems related to food safety. Since …
chromatography has played a vital role to solve many problems related to food safety. Since …
Detection of toxins involved in foodborne diseases caused by Gram‐positive bacteria
Bacterial toxins are food safety hazards causing about 10% of all reported foodborne
outbreaks in Europe. Pertinent to Gram‐positive pathogens, the most relevant toxins are …
outbreaks in Europe. Pertinent to Gram‐positive pathogens, the most relevant toxins are …
[HTML][HTML] A large travel-associated outbreak of iatrogenic botulism in four European countries following intragastric botulinum neurotoxin injections for weight reduction …
MB Dorner, H Wilking, M Skiba, L Wilk… - …, 2023 - eurosurveillance.org
In March 2023, 34 associated cases of iatrogenic botulism were detected in Germany (30
cases), Switzerland (two cases), Austria (one case), and France (one case). An alert was …
cases), Switzerland (two cases), Austria (one case), and France (one case). An alert was …
Applications and challenges of forensic proteomics
ED Merkley, DS Wunschel, KL Wahl… - Forensic science …, 2019 - Elsevier
Mass spectrometry-based proteomics has been a useful tool for addressing numerous
questions in basic biology research for many years. This success, combined with the …
questions in basic biology research for many years. This success, combined with the …
[HTML][HTML] Proteomic methods of detection and quantification of protein toxins
M Duracova, J Klimentova, A Fucikova, J Dresler - Toxins, 2018 - mdpi.com
Biological toxins are a heterogeneous group of compounds that share commonalities with
biological and chemical agents. Among them, protein toxins represent a considerable …
biological and chemical agents. Among them, protein toxins represent a considerable …
The use of Endopep–MS for the detection of botulinum toxins A, B, E, and F in serum and stool samples
SR Kalb, H Moura, AE Boyer, LG McWilliams… - Analytical …, 2006 - Elsevier
Botulinum neurotoxin (BoNT) causes the disease botulism, which can be lethal if untreated.
Previous work in our laboratory focused on developing Endopep–MS, a mass spectrometric …
Previous work in our laboratory focused on developing Endopep–MS, a mass spectrometric …
Botulism Diagnostics: From Clinical Symptoms to in vitro Assays
Botulinum neurotoxin (BoNT), which cause the deadly neuroparalytic disease, botulism, is
the most toxic substance known to man. BoNT can be used as potential bioterrorism agents …
the most toxic substance known to man. BoNT can be used as potential bioterrorism agents …
[HTML][HTML] Attomolar detection of botulinum toxin type A in complex biological matrices
K Bagramyan, JR Barash, SS Arnon, M Kalkum - PloS one, 2008 - journals.plos.org
Background A highly sensitive, rapid and cost efficient method that can detect active
botulinum neurotoxin (BoNT) in complex biological samples such as foods or serum is …
botulinum neurotoxin (BoNT) in complex biological samples such as foods or serum is …
[HTML][HTML] Sensing the deadliest toxin: technologies for botulinum neurotoxin detection
P Čapek, TJ Dickerson - Toxins, 2010 - mdpi.com
Sensitive and rapid detection of botulinum neurotoxins (BoNTs), the most poisonous
substances known to date, is essential for studies of medical applications of BoNTs and …
substances known to date, is essential for studies of medical applications of BoNTs and …