[HTML][HTML] Pharmacotherapy of anxiety disorders: current and emerging treatment options

A Garakani, JW Murrough, RC Freire, RP Thom… - Frontiers in …, 2020 - frontiersin.org
Anxiety disorders are the most prevalent psychiatric disorders and a leading cause of
disability. While there continues to be expansive research in posttraumatic stress disorder …

[HTML][HTML] Novel pharmacological targets in drug development for the treatment of anxiety and anxiety-related disorders

SB Sartori, N Singewald - Pharmacology & therapeutics, 2019 - Elsevier
Current medication for anxiety disorders is suboptimal in terms of efficiency and tolerability,
highlighting the need for improved drug treatments. In this review an overview of drugs …

Comparing the efficacy of benzodiazepines and serotonergic anti-depressants for adults with generalized anxiety disorder: a meta-analytic review

AF Gomez, AL Barthel, SG Hofmann - Expert opinion on …, 2018 - Taylor & Francis
Introduction: Generalized anxiety disorder (GAD) is a common form of anxiety disorder.
Selective serotonin reuptake inhibitors (SSRIs), serotonin and norepinephrine reuptake …

Melatonin as a potential approach to anxiety treatment

K Repova, T Baka, K Krajcirovicova, P Stanko… - International journal of …, 2022 - mdpi.com
Anxiety disorders are the most common mental diseases. Anxiety and the associated
physical symptoms may disturb social and occupational life and increase the risk of somatic …

Pharmacotherapy for anxiety disorders: from first-line options to treatment resistance

AJ Melaragno - Focus, 2021 - Am Psychiatric Assoc
In this review, the author examines the evidence for psychopharmacologic treatments
among adults for generalized anxiety disorder, panic disorder, and social anxiety disorder …

Pharmacological and psychological interventions for generalized anxiety disorder in adults: a network meta-analysis

TR Chen, HC Huang, JH Hsu, WC Ouyang… - Journal of Psychiatric …, 2019 - Elsevier
Generalized anxiety disorder (GAD) is a significant and common mental illness with a
lifetime prevalence of 3.7%. Regardless of the complexity of treatment decisions for GAD …

Comparative efficacy and acceptability of first-line drugs for the acute treatment of generalized anxiety disorder in adults: a network meta-analysis

H He, Y Xiang, F Gao, L Bai, F Gao, Y Fan, J Lyu… - Journal of psychiatric …, 2019 - Elsevier
The guide recommends SSRI and SNRI drugs as first-line treatments for generalized anxiety
disorder (GAD). Therefore, we aimed to update the evidence using network meta-analysis …

Vilazodone-phospholipid mixed micelles for enhancing oral bioavailability and reducing pharmacokinetic variability between fed and fasted states

HS El Said, A Lalatsa, AM Al-Mahallawi… - International Journal of …, 2022 - Elsevier
Despite the effectiveness and high tolerability of vilazodone (VLZ) as an antidepressant, its
use is still limited due to its poor solubility and food dependent absorption. This study aims to …

Efficacy of Silexan in subthreshold anxiety: meta-analysis of randomised, placebo-controlled trials

HJ Möller, HP Volz, A Dienel, S Schläfke… - European archives of …, 2019 - Springer
Subthreshold psychiatric disorders do not fully meet the diagnostic criteria of syndromal
disorders but may be associated with comparable disability. To investigate the anxiolytic …

[PDF][PDF] Panic disorder: a review of treatment options

M Ziffra - Ann Clin Psychiatry, 2021 - aacp.com
BACKGROUND: Panic disorder (PD) is a devastating illness, with numerous patients
experiencing significant functional disability and many not achieving full remission with first …