Oxidative stress is a pivotal point in the pathophysiology of COVID-19 and presumably also
in Long-COVID. Inflammation and oxidative stress are mutually reinforcing each other, thus …

The neurodegenerative condition known as Parkinson's disease (PD) is brought on by the
depletion of dopaminergic neurons in the basal ganglia, which is the brain region that …

A stroke is a serious life-threatening condition and a leading cause of death and disability
that happens when the blood vessels to part of the brain are blocked or burst. While major …

Accumulating evidence indicates a central role for epigenetic modifications in the
progression of stroke pathology. These epigenetic mechanisms are involved in complex and …

We previously showed that knockdown or deletion of Fos downstream transcript (FosDT; a
stroke-induced brain-specific long noncoding RNA) is neuroprotective. We presently tested …

Epigenetic alterations affect the onset of ischemic stroke, brain injury after stroke, and
mechanisms of poststroke recovery. In particular, DNA methylation can be dynamically …

Post‐stroke neuroinflammation is pivotal in brain repair, yet persistent inflammation can
aggravate ischemic brain damage and hamper recovery. Following stroke, specific …

Abstract The microRNA-21 (miR-21) levels in the brain are crucial in determining post-stroke
brain damage and recovery. The miR-21 exerts neuroprotection by targeting mRNAs that …

Vitamin C (Vc) plays a pivotal role in a series of pathological processes, such as tumors,
immune diseases, and neurological disorders. However, its therapeutic potential for tinnitus …

Despite significant advancements in achieving high recanalization rates (80%–90%) for
large vessel occlusions through mechanical thrombectomy, the issue of “futile …