Although human epidemics of influenza occur on nearly an annual basis and result in a
significant number of “excess deaths,” the viruses responsible are not generally considered …

Influenza is unique among the viruses in its capacity to vary. Because of antigenic variation,
it has proved impossible to control influenza by vaccination, and variation in virulence, host …

Two temperature sensitive mutants, ts3 and ts11, of the WSN (HON1) strain of influenza
virus, belonging to the same recombination group, have a 1000-to 10,000-fold lower …

Inhibition of the nuclear export of poly (A)-containing mRNAs caused by the influenza A virus
NS1 protein requires its effector domain. Here, we demonstrate that the NS1 effector domain …

A comparative analysis has been carried out on the infectivity of virus of several influenza A
strains grown in different host systems. Strains A/swine/Shope/31 (Hsw1N1), A/PR/8/34 …

Influenza hemagglutinin(HA) undergoes a conformational change that Induces viral fusion
with the cellular membrane. The structure of HA in the fusogenic state is unknown. We have …

Influenza viral complementary RNA (cRNA), ie, viral mRNA was radioactive when purified
from the cytoplasmic fraction of cordycepin-treated canine kidney cells that were incubated …

The infectivity of virions of the WSN strain of influenza A (A WSN) and the 1760 strain of
influenza B (B/1760) which possess their hemagglutinin in the form of the uncleaved HA …

The influenza A virus (IAV) HA protein must be activated by host cells proteases in order to
prime the molecule for fusion. Consequently, the availability of activating proteases and the …

As obligate intracellular parasites, viruses rely exclusively on the translational machinery of
the host cell for the synthesis of viral proteins. This relationship has imposed numerous …