Background Obtaining functional sperm cells is the first step to treat infertility. With the ever‐
increasing trend in male infertility, clinicians require access to effective solutions that are …

Sorting high-quality sperm with intact DNA, normal morphology, and active motility is crucial
for clinically assisted reproductive technology, which influences the success of treatment …

Sperm selection is an essential component of all assisted reproductive treatments (ARTs)
and is by far the most neglected step in the ART workflow in regard to technological …

Sperm motility is a natural selection with a crucial role in both natural and assisted
reproduction. Common methods for increasing sperm motility are by using chemicals that …

Isolating high-quality motile sperm cells is considered to be the main prerequisite for a
successful artificial pregnancy. Microfluidics has emerged as a promising platform capable …

Rheotaxis, as one of the main natural guidance mechanisms in vivo, has been used in
microfluidics to separate motile sperm. However, the lack of DNA integrity assessment and …

Over the past 4 decades our ability to maintain a viable human embryo in vitro has improved
dramatically, leading to higher implantation rates. This has led to a notable shift to single …

Active systems–including sperm cells, living organisms like bacteria, fish, birds, or active soft
matter systems like synthetic “microswimmers”–are characterized by motility, ie, the ability to …

Selection of high‐quality sperm is crucial to assisted reproduction. However, conventional
clinical methods for sperm selection are manual and prone to operator errors. This article …

Microfluidics offers tremendous opportunities to understand the underlying biology of
fertilization at the single-cell level and improve infertility management, however, its true …