Abstract Diabetic Foot Ulcers (DFUs) are major complications associated with diabetes and
often correlate with peripheral neuropathy, trauma and peripheral vascular disease. It is …

Introduction: The number of people with diabetes mellitus (DM) is estimated to exceed 640
million by the year 2040. Diabetic foot ulcer (DFU) is a debilitating illness that affects more …

Impaired wound closure is a growing medical problem associated with metabolic diseases
and aging. Immune cells play important roles in wound healing by following instructions from …

Introduction: Slow wound repair in diabetes is a serious adverse event that often results in
loss of a limb or disability. An advanced and encouraging vehicle is wanted to enhance …

The inhibition of dipeptidyl peptidase-4 (DPP4) significantly enhances the wound closure
rate in diabetic patients with chronic foot ulcers. DPP4 inhibitors are only prescribed for …

Diabetic wounds are a common complication in diabetes patients. Due to peripheral nerve
damage and vascular dysfunction, diabetic wounds are prone to progress to local ulcers …

Significance: Chronic skin wounds are a significant health problem around the world, often
leading to amputation and even death. Although persistent inflammation is a hallmark of …

Aim To compare the contribution of sodium-glucose cotransporter-2 inhibitors (SGLT2is)
with that of DPP4i or GLP-1ra toward lower extremity amputation rate. Methods Electronic …

Extracorporeal shockwave therapy (ESWT) has a significant positive effect to accelerate
chronic wound healing. This study investigated whether the vascular endothelial growth …

Dipeptidyl peptidase IV (DPP4) is a ubiquitous protease that can be found in membrane-
anchored or soluble form. Incretins are one of the main DPP4 substrates. These hormones …