Mitochondria as a cellular hub in infection and inflammation

P Andrieux, C Chevillard, E Cunha-Neto… - International journal of …, 2021 - mdpi.com
Mitochondria are the energy center of the cell. They are found in the cell cytoplasm as
dynamic networks where they adapt energy production based on the cell's needs. They are …

Molecular mechanisms of varicella zoster virus pathogenesis

L Zerboni, N Sen, SL Oliver, AM Arvin - Nature reviews microbiology, 2014 - nature.com
Varicella zoster virus (VZV) is the causative agent of varicella (chickenpox) and zoster
(shingles). Investigating VZV pathogenesis is challenging as VZV is a human-specific virus …

Potential anti-inflammatory and anti-cancer properties of farnesol

YY Jung, ST Hwang, G Sethi, L Fan, F Arfuso, KS Ahn - Molecules, 2018 - mdpi.com
Farnesol, an acyclic sesquiterpene alcohol, is predominantly found in essential oils of
various plants in nature. It has been reported to exhibit anti-cancer and anti-inflammatory …

Viral strategies for triggering and manipulating mitophagy

L Zhang, Y Qin, M Chen - Autophagy, 2018 - Taylor & Francis
Viral infection causes many physiological alterations in the host cell, and many of these
alterations can affect the host mitochondrial network, including mitophagy induction. A …

Manipulation of the innate immune response by varicella zoster virus

C Gerada, TM Campbell, JJ Kennedy… - Frontiers in …, 2020 - frontiersin.org
Varicella zoster virus (VZV) is the causative agent of chickenpox (varicella) and shingles
(herpes zoster). VZV and other members of the herpesvirus family are distinguished by their …

The gut microbiota metabolite urolithin B improves cognitive deficits by inhibiting Cyt C-mediated apoptosis and promoting the survival of neurons through the PI3K …

P Chen, F Chen, J Lei, G Wang, B Zhou - Frontiers in Pharmacology, 2021 - frontiersin.org
Background: Despite considerable advances in pharmacotherapy, more effective
therapeutic interventions for aging-related neurodegenerative disorders (NDs), such as …

Neuroprotective effects of gemfibrozil in neurological disorders: Focus on inflammation and molecular mechanisms

MS Ivraghi, MY Zamanian, R Gupta… - CNS Neuroscience …, 2024 - Wiley Online Library
Abstract Background Gemfibrozil (Gem) is a drug that has been shown to activate PPAR‐α,
a nuclear receptor that plays a key role in regulating lipid metabolism. Gem is used to lower …

Nuclear egress of herpesviruses: the prototypic vesicular nucleocytoplasmic transport

T Hellberg, L Paßvogel, KS Schulz, BG Klupp… - Advances in virus …, 2016 - Elsevier
Herpesvirus particles mature in two different cellular compartments. While capsid assembly
and packaging of the genomic linear double-stranded DNA occur in the nucleus, virion …

[HTML][HTML] T-cell immunity to human alphaherpesviruses

WJD Ouwendijk, KJ Laing, GMGM Verjans… - Current opinion in …, 2013 - Elsevier
Highlights•HSV T-cell immunity relies on multiple DC subsets and CD4/CD8 T-cell
cooperation.•Diverse CD4/CD8 responses to HSV-1 are accessible with genome-spanning …

Epstein-Barr virus (EBV) tegument protein BGLF2 promotes EBV reactivation through activation of the p38 mitogen-activated protein kinase

XQ Liu, JI Cohen - Journal of virology, 2016 - Am Soc Microbiol
Epstein-Barr virus (EBV) is a ubiquitous gammaherpesvirus associated with both B cell and
epithelial cell malignancies. EBV infection of B cells triggers activation of several signaling …