Portal hypertension is a clinical syndrome defined by a portal venous pressure gradient
exceeding 5 mm Hg. 1 Cirrhosis is the most common cause of portal hypertension in the …

The gut flora plays an important role in the pathogenesis of the complications of cirrhosis.
Cirrhotic patients are prone to develop bacterial infections, mainly the 'spontaneous …

They selected references within their field of expertise and experience and graded the
references according to the GRADE system. 1 The selection of references for the guideline …

Guidelines for clinical practice are intended to suggest preferable approaches to particular
medical problems as established by interpretation and collation of scientifically valid …

BACKGROUND & AIMS: Hepatic encephalopathy (HE) is associated with a poor prognosis.
Lactulose is used for the treatment of HE. There is no study on the prevention of recurrence …

Key points Hyperammonaemia occurs in hepatic, cardiac and pulmonary diseases with
increased muscle concentration of ammonia. We found that ammonia results in reduced …

Hepatic encephalopathy (HE) is a reversible syndrome of impaired brain function occurring
in patients with advanced liver diseases. The precise pathophysiology of HE is still under …

Mouse models of non-alcoholic fatty liver disease (NAFLD) are required to define
therapeutic targets, but detailed time-resolved studies to establish a sequence of events are …

Hepatic encephalopathy is a severe complication of cirrhosis that is related to the effects of
ammonia. Analysis of interorgan ammonia trafficking has identified an important role of …

Hepatic encephalopathy (HE) represents a broad continuum of neuropsychological
dysfunction in patients with acute or chronic liver disease and/or portosystemic shunting of …