Precision medicine is medicine optimized to the genotypic and phenotypic characteristics of an individual and, when present, his or her disease. It has a host of targets, including genes …
Pathway analysis is a set of widely used tools for research in life sciences intended to give meaning to high-throughput biological data. The methodology of these tools settles in the …
'Omic'technologies adopt a holistic view of the molecules that make up a cell, tissue or organism. They are aimed primarily at the universal detection of genes (genomics), mRNA …
The availability and utility of genome‐scale metabolic reconstructions have exploded since the first genome‐scale reconstruction was published a decade ago. Reconstructions have …
Chemical space—which encompasses all possible small organic molecules, including those present in biological systems—is vast. So vast, in fact, that so far only a tiny fraction of it has …
Recombinant protein production is a multibillion-dollar market. The development of a new product begins with the choice of a production host. While one single perfect host for every …
Metabolomics allows the simultaneous and relative quantification of thousands of different metabolites within a given sample using sensitive and specific methodologies such as gas …
The ability to sequence whole genomes has taught us that our knowledge with respect to gene function is rather limited with typically 30–40% of open reading frames having no …
The advent of functional genomics has enabled the molecular biosciences to come a long way towards characterizing the molecular constituents of life. Yet, the challenge for biology …