[Retracted] Intestinal Flora Balance Therapy Based on Probiotic Support Improves Cognitive Function and Symptoms in Patients with Alzheimer's Disease: A …

C Liu, X Guo, X Chang - BioMed Research International, 2022 - Wiley Online Library
Objective. The clinical value of intestinal flora balance therapy based on probiotic support in
improving cognitive function and symptoms of patients with Alzheimer's disease was to …

Deep learning-based identification of genetic variants: application to Alzheimer's disease classification

T Jo, K Nho, P Bice, AJ Saykin… - Briefings in …, 2022 - academic.oup.com
Deep learning is a promising tool that uses nonlinear transformations to extract features from
high-dimensional data. Deep learning is challenging in genome-wide association studies …

Age-Dependent Sex Differences in Perineuronal Nets in an APP Mouse Model of Alzheimer's Disease Are Brain Region-Specific

R Rahmani, N Rambarack, J Singh… - International Journal of …, 2023 - mdpi.com
Alzheimer's disease (AD) is the most common form of dementia, which disproportionately
affects women. AD symptoms include progressive memory loss associated with amyloid-β …

A multi-cohort study of the hippocampal radiomics model and its associated biological changes in Alzheimer's Disease

H Xia, X Luan, Z Bao, Q Zhu, C Wen, M Wang… - Translational …, 2024 - nature.com
There have been no previous reports of hippocampal radiomics features associated with
biological functions in Alzheimer's Disease (AD). This study aims to develop and validate a …

Dysregulated expression levels of APH1B in peripheral blood are associated with brain atrophy and amyloid-β deposition in Alzheimer's disease

YH Park, JM Pyun, A Hodges, JW Jang, PJ Bice… - Alzheimer's Research & …, 2021 - Springer
Background The interaction between the brain and periphery might play a crucial role in the
development of Alzheimer's disease (AD). Methods Using blood transcriptomic profile data …

Accelerated aging-related transcriptome alterations in neurovascular unit cells in the brain of Alzheimer's disease

Y Zhao, YZ Xie, YS Liu - Frontiers in aging neuroscience, 2022 - frontiersin.org
Alzheimer's disease (AD) is the most common cause of dementia with no effective therapies.
Aging is a dominant risk factor for AD. The neurovascular unit (NVU) plays an important role …

The plasma peptides of Alzheimer's disease

A Florentinus-Mefailoski, P Bowden, P Scheltens… - Clinical Proteomics, 2021 - Springer
Background A practical strategy to discover proteins specific to Alzheimer's dementia (AD)
may be to compare the plasma peptides and proteins from patients with dementia to normal …

Single-cell network biology characterizes cell type gene regulation for drug repurposing and phenotype prediction in Alzheimer's disease

C Gupta, J Xu, T Jin, S Khullar, X Liu… - PLoS Computational …, 2022 - journals.plos.org
Dysregulation of gene expression in Alzheimer's disease (AD) remains elusive, especially at
the cell type level. Gene regulatory network, a key molecular mechanism linking …

MicroRNA-target interaction regulatory network in Alzheimer's disease

A Turk, T Kunej, B Peterlin - Journal of personalized medicine, 2021 - mdpi.com
Alzheimer's Disease (AD) is a progressive neurodegenerative disorder and the most
common cause of dementia; however, early diagnosis of the disease is challenging …

[HTML][HTML] Brain-Region-Specific Differences in Protein Citrullination/Deimination in a Pre-Motor Parkinson's Disease Rat Model

A Mercer, M Sancandi, A Maclatchy… - International Journal of …, 2024 - mdpi.com
The detection of early molecular mechanisms and potential biomarkers in Parkinson's
disease (PD) remains a challenge. Recent research has pointed to novel roles for post …