Overcoming the translational barriers of tissue adhesives
For the past few decades, tissue sealants and adhesives have been developed as an
alternative to sutures and staples to close and seal wounds or incisions. These materials are …
alternative to sutures and staples to close and seal wounds or incisions. These materials are …
Integration of substrate-and flow-derived stresses in endothelial cell mechanobiology
CA Dessalles, C Leclech, A Castagnino… - Communications …, 2021 - nature.com
Endothelial cells (ECs) lining all blood vessels are subjected to large mechanical stresses
that regulate their structure and function in health and disease. Here, we review EC …
that regulate their structure and function in health and disease. Here, we review EC …
Age-related vascular stiffening: causes and consequences
JC Kohn, MC Lampi, CA Reinhart-King - Frontiers in genetics, 2015 - frontiersin.org
Arterial stiffening occurs with age and is closely associated with the progression of
cardiovascular disease. Stiffening is most often studied at the level of the whole vessel …
cardiovascular disease. Stiffening is most often studied at the level of the whole vessel …
3D printing based on cardiac CT assists anatomic visualization prior to transcatheter aortic valve replacement
Background 3D printing is a promising technique that may have applications in medicine,
and there is expanding interest in the use of patient-specific 3D models to guide surgical …
and there is expanding interest in the use of patient-specific 3D models to guide surgical …
Clinical grade manufacture of 3D printed patient specific biodegradable devices for pediatric airway support
H Ramaraju, AM Landry, S Sashidharan, A Shetty… - Biomaterials, 2022 - Elsevier
Implantable patient-specific devices are the next frontier of personalized medicine,
positioned to improve the quality of care across multiple clinical disciplines. Translation of …
positioned to improve the quality of care across multiple clinical disciplines. Translation of …
Evaluation of peak wall stress in an ascending thoracic aortic aneurysm using FSI simulations: effects of aortic stiffness and peripheral resistance
Purpose It has been reported clinically that rupture or dissections in thoracic aortic
aneurysms (TAA) often occur due to hypertension which may be modelled with sudden …
aneurysms (TAA) often occur due to hypertension which may be modelled with sudden …
Human dilated ascending aorta: mechanical characterization via uniaxial tensile tests
A Ferrara, S Morganti, P Totaro, A Mazzola… - Journal of the …, 2016 - Elsevier
Aneurysms of the ascending aorta (AsAA), ie, a progressive and localized dilatation of the
first part of the aorta, represent a severe life-threatening condition, often occurring with no …
first part of the aorta, represent a severe life-threatening condition, often occurring with no …
Pre-procedural fit-testing of TAVR valves using parametric modeling and 3D printing
Background Successful transcatheter aortic valve replacement (TAVR) requires an
understanding of how a prosthetic valve will interact with a patient's anatomy in advance of …
understanding of how a prosthetic valve will interact with a patient's anatomy in advance of …
[HTML][HTML] Regional biomechanical characterization of human ascending aortic aneurysms: Microstructure and biaxial mechanical response
The ascending thoracic aortic aneurysm (ATAA) is a permanent dilatation of the vessel with
a high risk of adverse events, and shows heterogeneous properties. To investigate regional …
a high risk of adverse events, and shows heterogeneous properties. To investigate regional …
Deciphering ascending thoracic aortic aneurysm hemodynamics in relation to biomechanical properties
The degeneration of the arterial wall at the basis of the ascending thoracic aortic aneurysm
(ATAA) is a complex multifactorial process, which may lead to clinical complications and …
(ATAA) is a complex multifactorial process, which may lead to clinical complications and …