Diabetic neuropathy: mechanisms to management

JL Edwards, AM Vincent, HT Cheng… - Pharmacology & …, 2008 - Elsevier
Neuropathy is the most common and debilitating complication of diabetes and results in
pain, decreased motility, and amputation. Diabetic neuropathy encompasses a variety of …

[HTML][HTML] The clinical impact of islet transplantation

P Fiorina, AMJ Shapiro, C Ricordi, A Secchi - American Journal of …, 2008 - Elsevier
Islet cell transplantation has recently emerged as one of the most promising therapeutic
approaches to improving glycometabolic control in diabetic patients and, in many cases …

Reduced progression of diabetic microvascular complications with islet cell transplantation compared with intensive medical therapy

DM Thompson, M Meloche, Z Ao, B Paty… - …, 2011 - journals.lww.com
Background. The effect of islet cell transplantation (ICT) on the progression of diabetic
microvascular complications is not well understood. Methods. We have conducted a …

Clinical application of microencapsulated islets: actual prospectives on progress and challenges

R Calafiore, G Basta - Advanced drug delivery reviews, 2014 - Elsevier
After 25 years of intense pre-clinical work on microencapsulated intraperitoneal islet grafts
into non-immunosuppressed diabetic recipients, the application of this procedure to patients …

Pathophysiology and pharmacotherapy of gastroparesis: current and future perspectives

JE Stevens, KL Jones, CK Rayner… - Expert opinion on …, 2013 - Taylor & Francis
Introduction: Gastroparesis is an important clinical disorder characterised by delayed gastric
emptying in the absence of mechanical outlet obstruction. Idiopathic, diabetes and …

Evaluation of polyneuropathy markers in type 1 diabetic kidney transplant patients and effects of islet transplantation: neurophysiological and skin biopsy longitudinal …

U Del Carro, P Fiorina, S Amadio… - Diabetes …, 2007 - Am Diabetes Assoc
OBJECTIVE—The purpose of this study was to evaluate whether islet transplantation may
stabilize polyneuropathy in uremic type 1 diabetic patients (end-stage renal disease [ESRD] …

Understanding the signaling pathways related to the mechanism and treatment of diabetic peripheral neuropathy

H Tang, A Jiang, J Ma, F Wang, G Shen - Endocrinology, 2019 - academic.oup.com
Worldwide, the most prevalent metabolic disorder is diabetes mellitus (DM), an important
condition that has been widely studied. Diabetic peripheral neuropathy (DPN), a …

Impact of islet transplantation on diabetes complications and quality of life

R Bassi, P Fiorina - Current diabetes reports, 2011 - Springer
Insulin represents a life-saving therapy for patients with type 1 diabetes but, despite
appropriate treatment, it prevents only partially long-term diabetic complications, while …

Axonopathy in peripheral neuropathies: Mechanisms and therapeutic approaches for regeneration

LM Landowski, PJB Dyck, JN Engelstad… - Journal of Chemical …, 2016 - Elsevier
Peripheral neuropathies (PNs) are injuries or diseases of the nerves which arise from varied
aetiology, including metabolic disease, trauma and drug toxicity. The clinical presentation …

Impact of pancreas transplantation on type 1 diabetes-related complications

C Gremizzi, A Vergani, V Paloschi… - Current opinion in organ …, 2010 - journals.lww.com
Impact of pancreas transplantation on type 1 diabetes-relate... : Current Opinion in Organ
Transplantation Impact of pancreas transplantation on type 1 diabetes-related …