Periostin: its role in asthma and its potential as a diagnostic or therapeutic target

W Li, P Gao, Y Zhi, W Xu, Y Wu, J Yin, J Zhang - Respiratory research, 2015 - Springer
Accumulating evidence shows that periostin, a matricellular protein, is involved in many
fundamental biological processes such as cell proliferation, cell invasion, and angiogenesis …

The interactions between autoinflammation and type 2 immunity: from mechanistic studies to epidemiologic associations

MK Sylvester, A Son, DM Schwartz - Frontiers in Immunology, 2022 - frontiersin.org
Autoinflammatory diseases are a group of clinical syndromes characterized by constitutive
overactivation of innate immune pathways. This results in increased production of or …

IL‐37 regulates allergic inflammation by counterbalancing pro‐inflammatory IL‐1 and IL‐33

A Schröder, LP Lunding, UM Zissler, C Vock… - Allergy, 2022 - Wiley Online Library
Background Children with asthma have impaired production of interleukin (IL) 37; in mice, IL‐
37 reduces hallmarks of experimental allergic asthma (EAA). However, it remains unclear …

Low-level laser therapy inhibits bronchoconstriction, Th2 inflammation and airway remodeling in allergic asthma

VR Silva, P Marcondes, M Silva, AB Villaverde… - Respiratory physiology …, 2014 - Elsevier
Low-level laser therapy (LLLT) controls bronchial hyperresponsiveness (BHR) associated
with increased RhoA expression as well as pro-inflammatory mediators associated with NF …

IL-1β: a key modulator in asthmatic airway smooth muscle hyper-reactivity

Z Liao, H Xiao, Y Zhang, RS Tong… - Expert review of …, 2015 - Taylor & Francis
Asthma is a chronic inflammatory disorder of the airway. It is characterized by airway hyper-
reactivity, which can be attributed to the chronically inflamed airway. However, the molecular …

IL-13 immunotoxin accelerates resolution of lung pathological changes triggered by silica particles in mice

TPT Ferreira, ACS de Arantes… - The Journal of …, 2013 - journals.aai.org
Instillation of silica into the lungs of rodents results in pathological changes that strongly
mimic human silicosis, an occupational lung disease marked by restrictive airway …

Homeostatic glucocorticoid signaling in airway smooth muscle: A roadmap to asthma pathogenesis

MM Grunstein - Frontiers in Endocrinology, 2023 - frontiersin.org
Homeostasis is the self-regulating process by which the body maintains internal stability
within a narrow physiological range (ie,“normality”) as it dynamically adjusts to disruptive …

[HTML][HTML] Inflammasome activity in non-microbial lung inflammation

JL Ather, RA Martin, K Ckless… - Journal of environmental …, 2014 - ncbi.nlm.nih.gov
The understanding of interleukin-1 (IL-1) family cytokines in inflammatory disease has
rapidly developed, due in part to the discovery and characterization of inflammasomes …

Electroacupuncture Attenuates Ovalbumin‐Induced Allergic Asthma via Modulating CD4+CD25+ Regulatory T Cells

Y Kwon, SH Sohn, G Lee, Y Kim, H Lee… - Evidence‐Based …, 2012 - Wiley Online Library
A mouse pulmonary hypersensitivity experimental model that mimics human asthma was
developed, and electroacupuncture (EA) treatment was shown to reduce allergic …

Inflammasome in the pathogenesis of pulmonary diseases

F Xu, Z Wen, X Shi, J Fan - Inflammasomes: Clinical and Therapeutic …, 2018 - Springer
Lung diseases are common and significant causes of illness and death around the world.
Inflammasomes have emerged as an important regulator of lung diseases. The important …